• Certified Beelzemon simp • INTP • Finest potato on field • He, she, it, idk, you choose. Call me anything •
68 posts
Latest Posts by creasion616 - Page 2
Drawing of my OC Enigma
Aaaaaaaaa, canon long haired Than
Omg canon long hair Than
Digital rendition of my last drawing of Arata XD
MekaMeka 5k subs!!
Congratulations for VTuber Yasumu Ameka for 5K subscribers!!
Waiting for the next Quran recital and talks next year XD
snek bodi confirmed
hey guys i called my uncle who works at supergiant and he told me the canon dusa body design
In the name of Hades, I accept this Mantle!
Título: 404 Música, letra y vídeo: PinocchioP Vídeo original: YouTube - Nicovideo Traducido desde la traducción oficial al inglés Letra:
Keep reading
Art dump!
From the song 404 by PinocchioP
Arata Sanada, requested by my sister
Just play Hades a few days ago and I officially call this man my spirit animal lel
Started playing Hades a few days ago, already broke into freedom in Greece. Also, Hypnos is my spirit animal and you can't deny this fact
Christmas event banner gacha
Cute election winner
And also...
Wanna know if Pino HNM will be out on gran colo next month...
To sleep deeply: the brainstem neurons that regulate non-REM sleep
Mammals experience rapid eye movement (REM) and non-REM (NREM) sleep. While the hypothalamus and brainstem are known to be a critical regulators of sleep, the precise mechanism is not fully understood. New work in mice has found that a widely distributed network of neurotensinergic neurons regulates NREM sleep, which also implicates a critical role of the neuropeptide neurotensin.
A normal sleep architecture is crucial for physical and cognitive health, and disruption of REM/NREM sleep can therefore have serious consequences. While several brain areas including the hypothalamus are known to be essential for NREM sleep, comparatively little is known about how the brainstem controls NREM sleep. Previous work has found that a subregion of the brainstem, the sublaterodorsal tegmental nucleus (SubLDT), regulates both REM and NREM sleep. Researchers at the University of Tsukuba therefore targeted this area to identify NREM sleep-promoting neurons, and found that a wide network of neurotensin-producing neurons is involved in NREM sleep regulation. The article was published in Current Biology last month.
“Using microarray analyses, we measured the expression levels of several genes in the mouse SubLDT,” says Associate Professor Yu Hayashi, corresponding and last author of the study. “A subset of these SubLDT neurons had a high, selective expression of the gene Nts, which encodes the neuropeptide neurotensin. Artificial activation of these SubLDT neurons promoted NREM sleep, which confirmed the role of Nts-expressing neurons in NREM sleep.”
NREM sleep-promoting neurons were also found in three other brainstem structures that have not previously been proven to be involved in sleep regulation (the dorsal deep mesencephalic nucleus, periaqueductal gray, and medial vestibular nucleus). Neurons in these regions also expressed Nts. Furthermore, direct administration of neurotensin itself induced NREM sleep-like brain activity.
“Our findings not only provide insights about brainstem involvement in NREM sleep promotion, but also highlight the key role of neurotensin,” says Mitsuaki Kashiwagi, first author. “It will be interesting to see whether Nts-expressing neurons contribute to the co-ordination between sleep and other known functions of neurotensin signaling, such as pain and metabolism. The response of Nts-expressing neurons also differed according to the time of day, so the influence of the circadian rhythm on these neurons should be studied.”
More broadly, these results could tell us something about the evolution of the complex sleep architecture of mammals. Future work could examine whether similar Nts-expressing neurons are also present in vertebrates, which do not experience REM and NREM sleep.
Cuci Suci Lima Kali Dapat Satu Kali Cuci Free
bonus:
bonus again:
chimken nuggies??
You’re no ‘winner winner’ and this is no ‘chicken dinner’ - out of my court, you’re going to prison for 25 years
Finally digivolved into Shine Greymon BM
Yolo pull is at it again today
Got both of them in Mirage Gaogamon BM banner just now. I am glad to decide to pull today.
digimanga / digivice
Hshshhshshshshs.... Am I dreaming right now???
My dragon sugar dad-- I mean dragon soulmate get me Playstore credits!! He just suddenly messaged me the code this morning asdfghjkl....
I CAN BUY MY BOI PINOOOOOOOO!!!!! -cries-
Aaaaaaagh, instant noodles!!
Asgdjakajdhjskdjhajaghghghhhhshshsh
Always laughing at this scene
friendly reminder that
One of countless dynamic that kill me XD
A favorite character dynamic / story arc
Eeeeeeeeeee, this is so cute. I'm new to tumblr so I didn't have someone to tag -cri-
I'm tagging anyone who want to do this!!! (｡•̀ᴗ-)✧
PICREW!
So i found this awesome picrew,,,,and I’m gonna start a picrew chain :D
Picrew
Here’s mine
tagging @holding-infinity-and-a-book @anxious-ace-dork @tothestarsndback @slytherclaw-lair @padfootalltheway and anyone else who wants to do it :)
kirby after swallowing sephiroth:
Using this pic as my wallpaper was a mistake (or not)
I love this fat purple ghost so much and this fact proves that it's very hugable
It’s his canonical size
