sticks My Entire Head Inside His Huge Mouth

*sticks my entire head inside his huge mouth*

The cordyceps ‘vaccine’ in the Last of Us is bullcrap

I know this is just a game and maybe the science and medical advancement in the game is different from the real world, but if we apply what we know in real life about infectious diseases and preventative medicine in real life, the Fireflies probably wouldn’t be able to make a ‘vaccine’ and would have killed Ellie and destroyed the possibility of a cure for nothing. Here’s why:

1. In the real world, we do not have vaccines for fungal infection. Firstly, because fungal infection are super rare and mostly only affect those with compromised immunity. Secondly, anti-fungal medications are usually very effective against fungal infection so the medical field was never pushed to develop a vaccine for any fungal infections. I’m not saying that developing a vaccine for fungal diseases is impossible, but right now we don’t have any successful fungal vaccine and I highly doubt that in a post-apocalyptic world, this ONE doctor with insufficient equipment would be able to make a vaccine out of Ellie’s sample.

2. A vaccine prevents someone from developing disease after contracting the pathogen, it has no effect on people who already contracted the fungus and developed disease. So it is not a ‘cure’.

3. To make a vaccine, you use a weakened version of the pathogen, or a similar pathogen that does not cause disease in your target species. If they want to make a vaccine for the cordyceps fungus, they could have easily used fungal sample from the infected and engineer a vaccine from it. They didn’t have to kill Ellie for it.

4. In the game, Ellie was unconscious before she entered the Fireflies hospital and remained unconscious throughout the entire time she was there. So, either all the tests and decisions happened in a very short time or they kept her under with anaesthetic drugs. But since Joel was there as well and he woke up to them telling him they are going to kill Ellie, I would say they made a decision to kill ellie in a very short time. The problem is, they only had her for such a short time and they obviously have not studied Ellie before they got her, how in the world could they possibly figure out what makes Ellie immune so quickly?!

5. In the game, they claimed that the reason Ellie is immune is because the fungus has mutated inside of her. But really, there is no way the doctor would know the fungus has mutated unless he got a sample of the fungus. In the game it looked like all they have was an MRI scan. Just using imaging is NOT sufficient to identify a mutation, you would need to look at the sample microscopically and DNA test it. If that doctor somehow got his hand on some of the fungal samples from Ellie and found a mutation, why would he need to cut her brain open? That make absolutely no sense?!

6. They can’t prove the reason that Ellie is immune due to a mutated fungus. To prove the theory, they would need to inoculate the mutated pathogen in a test subject (usually would start with a petri dish of target cells, and then a lab animal) and look for changes. They obviously haven’t done it so how can they be so sure about this and would bet the life of a teenage girl on it?

7. To make a cure, killing Ellie is the VERY LAST thing they should do. Hell, it shouldn’t even be on a list. If they want to make a cure, the VERY FIRST thing they should have done is take her blood and test her plasma. The plasma of our blood contains antibodies, the thing that fights off infections. If I’m the doctor/scientist, knowing Ellie is immune, her plasma is the first thing that I would look at. Because if someone is immune to a disease, that means their body has developed effective antibodies against said infection, and these antibodies will remain in their circulation for some time, and even if the level isn’t enough, upon reintroduction of the pathogen, her antibodies level would skyrocket. Using her plasma, they can potentially treat people after they have been exposed to the fungus. But yea, her plasma would be the cure so killing her is stupid.

8. In this vast population of humans, it is highly impossible that Ellie is the only one who is immune.

I know this is just a game but I’m way too emotionally invested in this. And the fact that they made it sounds like Abby’s father was going to develop a cure and that he is a saint, is absolute bullcrap. He was going to kill an innocent girl and the last hope for a cure for NOTHING. Joel did the right thing by saving her.

Weird Questions

If I’m somewhere where there are Educational Personell (Museum Docents, Q&A zookeepers, Park Rangers, Public School Teachers, Professors etc.) I have a question I like to ask them:

“What’s the weirdest question someone’s ever asked you?”

I say weird and not Dumb becuase even buckwild questions can have important answers, but whoever I ask it too usually has to think about it for a bit, then comes out with something different every time. And I love every single answer becuase it just warms my heart out there to know people are trying to understand the world a bit better, no matter how limited thier starting point. A collection of favorites so far:

Art Museum Host: “A man once asked me “Can you help me find someone and if you can’t can you find someone who can?” Which I always thought would be a great title for an Artwork.”

Park Ranger: “I’m so glad the Japanese couple asked me “Is bear spray like mosquito spray and it goes on the jacket, or on the bear?” instead of just trying it.”

Zookeeper: “A man once pointed at the live red-tailed hawk I had out for a demo and asked me “Aren’t those extinct?” We eventually figured out he meant “Endangered” but I hear that question every time I see a redtail now.”

Primary School Teacher: “About every other year a student asks me what part of the school I sleep in at night, because clearly I live here. I tell them I sleep under the bleachers in the gym but it’s actually the Nurse’s office.”

Professor: “A student asked me “So how do I use this in a conversation when my aunt is wine-drunk at thanksgiving and being a jerk again?” Which honestly is a fair question about philosophy and really changed how I teach rhetoric.”

Natural History Docent: “A woman once asked me what the difference between a Million and a Billion was. Kinda pieced together that she’d just left her church for her safety, and was learning about Earth’s Natural History for the first time. Nobody else was there because it had been snowing, so I walked her through the Hall Of Time and answered as many questions as I could. She was bewildered, but really trying. It always struck me as a really brave thing, to try to understand all of that while fresh out of a dangerous situation. I hope it helped.”

Forensic Scientist: “People ask me how to commit murder all the time, but if you really hate someone, stealing thier identity causes much more suffering and is a lot harder to get caught at. A guy did ask me if working at a body farm was creepy and did not like that it was ok until you learned that decayed human fingers are a deer’s favorite midwinter snack.”

Zookeeper: “People call us becuase they think they’ve found an escaped animal all the time, or they think they’re neighbor’s husky is a wolf. One guy asked me if his dog was part hyena because it had spots. But that one guy really did have a Tiger in his toolshed that one time so we try to take them seriously.”

Meteorologist: “A guy once emailed me about how hard you’d have to fan a tornado to make it start spinning in the other direction and included a picture of him holding up a box fan at an approaching tornado. We printed it out for the work fridge.”

Park Ranger: “I was giving a talk on the Yellowstone Supervolcano and a guy asked if, after it errupted, the earth would be ‘hollowed out’. I suppose I was just relieved that he understand that the earth isn’t flat.”

Primarcy Shcool teacher: “A student once asked me where she could sell her bones online so she could by a dog. Which? Same.”

Natural History Docent: “A guy asked us ‘If I had a time machine, and managed to kill and cook a T-Rex, what would it have tasted like?’ and every paleontologist on staff deciced to take him seriously. They did research to learn about fat distribution, and read up on culinary science to learn what flavors meat, even did chemical analysis on the bones. They concluded that it’d be Tough (no evidence of juicy fat pockets), bitter (carnivores tend to taste foul) and would probably kill him, because heavy metals travel up the food chain and T-Rex accumulated a lot of the cadmium that was in the dirt in the late cretaceous. Wrote him a letter with our findings and he sent us back a drawing of him and his buddies cooking a T-Rex over a fire and all of them throwing up and dying, and it’s my favorite drawing in the whole world.”

85K notes View Post

mc-moss

4 years ago