Scientists from BGI-Research developed a new version of the Cultivated Genome Reference (CGR), a repository of high-quality draft genomes of the human gut microbiome. The current version of CGR, which is CGR2, has been further expanded to incorporate numerous high-quality draft genomes generated from cultivated bacteria. CGR2 classifies previously unidentified species and uncovers the functional and genomic diversity of bacterial strains. An in-depth analysis of carbohydrate-active enzymes (CAzymes) reveals the phyla with the largest and most diverse repertoires of these enzymes. CGR2 also enabled the identification of genes involved in the synthesis of secondary metabolites in the gut microbiome. The unraveling of the gut microbiome genomic landscape will enable the development of therapeutics and provide a deep insight into the evolution of the human gut microbiome.
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Mangrove box jellyfish (Tripedalia cystophora) is a small species of box jellyfish, native to the Caribbean Sea and the Central Indo-Pacific, presenting a simple nervous system. But despite tiny, researchers have demonstrated present the ability to learn by association. Although has no central brain, and being the size of the finger-tip, this box jelly can be trained to associate the sensation of bumping into something with a visual cue, and to use the information to avoid future collisions.
In the wild, the Mangrove box jellyfish forage for tiny crustaceans between the roots of mangroves. To mimic this environment, researchers placed the box jellies in cylindrical tanks that had either black and white or grey and white vertical stripes on the walls. To the jellyfish, the dark stripes looked like mangrove roots in either clear or murky water. In the āmurky waterā tanks, the jellyfish bumped into the wall because their visual system couldnāt detect the grey stripes very clearly. But after a few minutes, they learnt to adjust their behaviour, pulsing rapidly to swim away from the wall when they got too close, this state learning is based on the combination of visual and mechanical stimuli in simple animals with no brain.
The learning process, in difference with vertebrate animals, doesnt occurs in a central neuronal organs, but instead in a small organs named rhopalial nervous system, which act as learning center, in which the jelly combines visual and mechanical stimuli during operant conditioning.
Main image: An adult specimen of the box jellyfishĀ T.Ā cystophora., showing where is located one of the four sensory structures named rhopalia, which includes two lens eyes. Each rhopalium also contains a visual information processing center.
Reference (Open Access): Bielecki et al., 2023. Associative learning in the box jellyfish Tripedalia cystophora.Ā Current Biology.
what is she doing!! ~~~~ why!!!
āBats have attracted great attention as a likely reservoir of the SARS-CoV-2 virus responsible for the COVID-19 pandemic,ā says Professor Wang Lin-Fa of the Duke-NUS Emerging Infectious Diseases (EID) Programme and senior author of the study in the journal Cell. āBut this unique ability to host yet survive viral infections could also have a very positive impact on human health if we can understand and exploit how they achieve this.ā
The research is focused on multi-protein complexes called inflammasomes that are responsible for the overactive inflammation that causes serious symptoms in many diseases. Inflammasomes are also implicated in functional decline in aging.
The researchers discovered that a bat protein called ASC2 has a powerful ability to inhibit inflammasomes, thereby limiting inflammation.
āThis suggests that the high-level activity of ASC2 is a key mechanism by which bats keep inflammation under control, with implications for their long lifespan and unique status as a reservoir for viruses,ā explains Matae Ahn, first author and co-corresponding author of the study and an adjunct research fellow with the EID Programme and the SingHealth Duke-NUS Medicine Academic Clinical Programme.
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Fat Cell diagram for a college science class in 2022, rehearse for your science quiz here
There are few places on Earth as isolated as Trindade island, a volcanic outcrop a three- to four-day boat trip off the coast of Brazil.
So geologist Fernanda Avelar Santos was startled to find an unsettling sign of human impact on the otherwise untouched landscape: rocks formed from the glut of plastic pollution floating in the ocean.
Santos first found the plastic rocks in 2019, when she traveled to the island to research her doctoral thesis on a completely different topicālandslides, erosion and other āgeological risks.ā
She was working near a protected nature reserve known as Turtle Beach, the worldās largest breeding ground for the endangered green turtle, when she came across a large outcrop of the peculiar-looking blue-green rocks.
Intrigued, she took some back to her lab after her two-month expedition.
Analyzing them, she and her team identified the specimens as a new kind of geological formation, merging the materials and processes the Earth has used to form rocks for billions of years with a new ingredient: plastic trash.
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Kinda wild how all the bacteria in your gut have their own DNA, like they are not related to you, they don't have your DNA in them, they are just separate lil beings that just live in your gut. They don't even know they live inside a human, but you are their whole universe
Punctelia reddenda
This gorgeous foliose lichen grows in rosettes up to 6 cm in diameter. The upper surface is gray-green to yellow-green with white, punctiform (point or dot like) pseudocyphella which turn into soralia which produce granular or nodular soredia. The lower surface is black toward the center and lightens to brown near the rounded margins of the overlapping lobes. P. reddenda grows on mossy tree trunks and rock in Africa, Macaronesia, North and South America, and Europe.
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still amazes me that scientists were just like what if we shot cells with dna coated mini bullets really really hard to insert that dna into the genome. and somehow that fucking worked
Comatricha nigra
by andysandsphotography
Pterocarpus AngolensisĀ is a tree native to South Africa. Itās also commonly known as the bloodwood tree due to the fact that when itās chopped or damaged, a deep red sap which looks eerily similar to blood, seeps from the tree. In fact, the purpose of the sap is to coagulate and seal the wound to promote healing, much like blood.