I Feel Like A Lot Of The Younger Group Of People On The Internet Especially Those Who Became Online In

Attention people who don’t have horses:

Sorry to break in with this on a very much Sherlock-only kind of blog- I promise not to make a regular thing of this, but this is something that’s happened TWICE now. 

This is Beyli. He’s a two-month old foal and he’s adorable. He belongs to a friend of the family. 

So adorable, in fact, that a member of the public spent a nice afternoon feeding him. You feed the ducks and that’s ok. right? It’s a nice thing to do. 

They fed him turnip. He choked and gave himself a stomachache as a result.

The problem is that horses can’t really burp and horses can’t vomit. Their digestive systems are fine-tuned and when they go wrong, they go really wrong. Colic in horses is difficult to treat and in Beyli’s case, like many others, proved to be insurmountable. With pain medicine not working, after 4 hours of doing their best with no improvement, the vet called time on his suffering rather than let him go on to a very slow and painful end. 

A horse needlessly suffered and died because someone fed him the wrong thing. They weren’t necessarily malicious, they were just hugely ignorant. And worse, they were hugely entitled. There were already signs asking people not to feed the animals. As I said, this has now happened TWICE to the same family, and they’re by no means alone. 

PLEASE Don’t feed horses that don’t belong to you. 

Horses can have disorders, diabetes, allergies and dietry requirements and you have NO IDEA if what you’re giving them is acceptable or not. Even ‘safe’ things like carrot and apple could be ‘wrong’ for this particular horse. Grass clippings? Not okay. Grain? Not okay for a horse that hasn’t been regularly eating it. 

Don’t assume. i have seen walkers pull up random plants and offer them over the fence INCLUDING TOXIC, DEADLY weeds like ragwort. I’ve seen horses offered dog-biscuits and bread. I’ve heard of horses being regularly fed by strangers thinking they were being under-fed, when the horse in question was on a vet-given diet to control weight and other conditions. 

Don’t feed horses that don’t belong to you even little treats and things like sugar cubes because it gives them bad manners. They start biting and harassing people. It’s bad for their teeth and too much sugar is terrible for them.

In some places if the owner has liability insurance, if you can be identified, YOU will be legally responsible for the vet’s bills. And if you’re thinking ‘well, they’d never identify me’, then that’s besides the point. 

Please. You wouldn’t feed someone’s dog without asking, I hope. You definitely wouldn’t feed someone else’s child. 

TL;DR: Don’t feed other people’s horses. You can make them SERIOUSLY ill. Treat animals in fields like animals at the zoo: you’re welcome to look, but don’t meddle with their care. 

PLEASE DON’T FEED OTHER PEOPLE’S HORSES. 

Good News Network

Researchers Discover New Mechanism for Rapid Liver Regeneration to Restore Damaged Livers

Researchers discovered a mechanism after acute liver damage occurs—and it could lead to treatments for those with severe liver problems.

"Researchers at the National Cancer Research Centre in Spain (CNIO) have discovered a mechanism that is triggered just minutes after acute liver damage occurs—and it could lead to treatments for those with severe liver problems.

The avenues for future treatments of liver damage include a diet enriched with the amino acid glutamate.

“Glutamate supplementation can promote liver regeneration and benefit patients in recovery following hepatectomy or awaiting a transplant,” wrote the authors in a paper published in ‘Nature’.

The liver is a vital organ, crucial to digestion, metabolism, and the elimination of toxins. It has a unique ability to regenerate, which allows it to replace liver cells damaged by the very toxins that these cells eliminate.

However, the liver stops regenerating in cases of diseases that involve chronic liver damage–such as cirrhosis—and such diseases are becoming increasingly prevalent, associated with poor dietary habits or alcohol consumption. So activating liver regeneration is key to treating the disease.

Learning to activate liver regeneration is therefore a priority today, to benefit patients with liver damage and also those who’ve had part of their liver cut out to remove a tumor.

The research has discovered in animal models this previously unknown mechanism of liver regeneration. It is a process that is triggered very quickly, just a few minutes after acute liver damage occurs, with the amino acid glutamate playing a key role.

“Our results describe a fundamental and universal mechanism that allows the liver to regenerate after acute damage,” explained Nabil Djouder, head of the CNIO Growth Factors, Nutrients and Cancer Group and senior author of the study.

A “complex and ingenious” perspective on liver regeneration

Liver regeneration was known to occur through the proliferation of liver cells, known as hepatocytes. However, the molecular mechanisms involved were not fully understood. This current discovery is very novel, as it describes communication between two different organs, the liver and bone marrow, involving the immune system, according to a CINO news release.

The results show that liver and bone marrow are interconnected by glutamate. After acute liver damage, liver cells, called hepatocytes, produce glutamate and send it into the bloodstream; through the blood, glutamate reaches the bone marrow, inside the bones, where it activates monocytes, a type of immune system cell. Monocytes then travel to the liver and along the way become macrophages – also immune cells. The presence of glutamate reprograms the metabolism of macrophages, and these consequently begin to secrete a growth factor that leads to an increase in hepatocyte production.

In other words, a rapid chain of events allows glutamate to trigger liver regeneration in just minutes, through changes in the macrophage metabolism. It is, says Djouder, “a new, complex and ingenious perspective on how the liver stimulates its own regeneration.”

The research also clarifies a previously unanswered question: how the various areas of the liver are coordinated during regeneration. In the liver, there are different types of hepatocytes, organized in different areas; the hepatocytes in each area perform specific metabolic functions. The study reveals that hepatocytes producing a protein known as glutamine synthetase, which regulates glutamate levels, play a key role in regeneration.

According to the CNIO group, when glutamine synthetase is inhibited, there is more glutamate in circulation, which accelerates liver regeneration. This is what happens when the liver suffers acute damage: glutamine synthase activity decreases, blood glutamate increases, and from there, the connection with the bone marrow is established, reprogramming macrophages and stimulating hepatocyte proliferation.

Possible therapeutic applications

The experiments have been carried out in mice, but the results have been tested with bioinformatics tools, using databases of mouse and human hepatocytes.

According to Djouder, “dietary glutamate supplementation may simply be recommended in the future after liver extirpation, and also to reduce liver damage caused by cirrhosis.”

The first author of the paper, CNIO researcher María del Mar Rigual also wants future research to explore using glutamate supplements in humans who have undergone liver resection for tumor removal."

-via Good News Network, March 30, 2025

Stop Making Psychosis A Villainous Trait Challenge

Source

Transcript:

“BREAKING: A constitutional amendment has been filed allowing President Trump to seek a 3rd term in office.

"No person shall be elected to the office of the President more than three times, nor be elected to any additional term after being elected to two consecutive terms, and no person who has held the office of President, or acted as President, for more than two years of a term to which some other person was elected President shall be elected to the office of the President more than twice."

It was filed by Congressman Andy Ogles (R-TN).

Don’t let this slip by unnoticed. This is not just “one extra term”, it’s a warning shot. It’s a red flag. It’s an omen.

They are slowly turning up the heat in the pan. Do not be the frog who sits denying it’s getting hotter.

One extra term will become two, two will become three, and three will eventually give way to lifelong reign of each president.

Fight. Fight for God’s sake.

Contact your local representative of congress. Convince them we do not want this.

We are going to end up in a dictatorship.

@ikiyou

Please help spread this. I don’t usually get political and I don’t usually ask for assistance but this is important and you have more reach.

if you or anyone you know you needs an abortion, call 1-800-230-Plan, or go to http://AbortionFinder.org

ok, because i just saw a terrible take, i feel compelled to say that there is no "fic market" to "oversaturate" in fandom. good gravy.

I know there’s an existing post somewhere, but here’s the list of OBGYNs in the USA and other countries that will perform tubal ligation (aka female sterilization) without arguing with you

Google Docs

Gynecologists who will perform a tubal sterilization

Gynecologists who will perform a tubal sterilization