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Most of the loud, articulate and visible people in the mental illness related communities are people who could, admittedly with outdated terminology, be considered "high functioning."

This makes sense, considering that it takes a certain level of ability and energy to get properly involved in activism of any kind. But here's a reminder not to forget and exclude the rest of us.

Don't forget about the people with cognitive impairments and intellectual disabilities and learning difficulties and don't alienate them by insisting that "just because we're mentally ill doesn't mean we're not intelligent."

Don't forget about the people in institutions like group homes and psych wards and don't alienate them by talking about how "mental illness doesn't mean you have to be locked up in an institution."

Don't forget about the people who are unemployed and/or uneducated and are forced to rely economically on welfare or their loved ones and don't alienate them by saying things like "mental illness should not affect your ability to provide for yourself."

Don't forget about all the people with chronic illnesses and all the people who are treatment resistant and don't alienate them by saying that a full recovery is always inevitable and realistic.

Don't forget about the people who are visibly mentally ill and who can't ever pass as neurotypical and don't alienate them by saying things like "mentally ill people are always just like everyone else."

Every mentally ill person struggles in different ways and I don't mean to invalidate anyone, but I am tired of seeing the more functional people throw less functional people under the bus in the name of activism and reducing stigma.

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Scientists discover schizophrenia gene roles in brain development

A USC research team identified 150 proteins affecting cell activity and brain development that contribute to mental disorders, including schizophrenia, bipolar condition and depression.

It’s the first time these molecules, which are associated with the disrupted-in-schizophrenia 1 (DISC1) protein linked to mental disorders, have been identified. The scientists developed new tools involving stem cells to determine chemical reactions the proteins use to influence cell functions and nerve growth in people.

“This moves science closer to opportunities for treatment for serious mental illness,” said Marcelo P. Coba, the study author and professor of psychiatry at the Zilkha Neurogenetic Institute at the Keck School of Medicine of USC.

The findings appear in Biological Psychiatry.

Schizophrenia affects less than 1 percent of the U.S. population, but has an outsized impact on disability, suicide and premature deaths.

The DISC1 gene was linked to schizophrenia nearly 20 years ago. It controls how nerve cells called neurons develop, as well as how the brain matures. DISC1 also directs a network of signals across cells that can contribute to the disease. Scientists say errors in these chemical reactions contribute to schizophrenia.

But the identity of proteins that DISC1 can regulate is poorly understood, prompting the USC researchers and colleagues from the State University of New York Downstate Medical Center to undertake the research. The challenge was to simulate conditions inside the human brain, Coba explained.

Using stem cells, they conducted assays resembling habitat where DISC1 does its work. They then used gene editing to insert a molecular tag on DISC1, allowing them to extract it from brain cells and identify the proteins with which it associates.

Identifying the proteins that interact with DISC1 in brain cells could lead to understanding how the risk factors for psychiatric diseases are connected to specific molecular functions, Coba explained. The discovery enables researchers to determine specific processes that differ in patients suffering from specific mental illnesses.

“This gives researchers specific trails to follow within cells from both healthy patients and those diagnosed with disorders,” Coba said.

Schizophrenia research

Schizophrenia is one of the top 15 leading causes of disability worldwide. People with schizophrenia live an average of nearly 29 years less than those without the disorder, according to the National Institutes of Mental Health (NIMH).

The illness is often accompanied by conditions such as heart disease and diabetes, which contribute to the high premature mortality rate among people with schizophrenia. About 5 percent of people with schizophrenia die by suicide, a rate far greater than the general population, with the highest risk in the early stages of illness, according to the NIMH.

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Two important Method  of  MEDITATION.

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"In order to move on, you must understand how you felt, and why you felt it." Mitch Albom

Quite Simple When You Think About It