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Study discovers that mitochondria transmit signals in the immune and nervous systems

The new study has revealed that mitochondria play a crucial role in the regulation of the NF-κB signaling pathway.

Mitochondria are primarily known as the powerhouse of the cell. However, these cellular organelles are required not only for providing energy: Professor Konstanze Winklhofer and her group at the Faculty of Medicine at Ruhr University Bochum, Germany, recently discovered that mitochondria play an important role in signal transduction in innate immune pathways.

They regulate a signaling pathway that helps to eliminate pathogens, but can cause damage through inflammation upon overactivation. The research team published their findings in the EMBO Journal.

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Reblog and write the opposite of your URL

thatwasnotveryravenofyou → itisextremelypigeonofthem

Like humans, these big-brained birds may owe their smarts to long childhoods

Human beings typically don’t leave the nest until well into our teenage years—a relatively rare strategy among animals. But corvids—a group of birds that includes jays, ravens, and crows—also spend a lot of time under their parents’ wings. Now, in a parallel to humans, researchers have found that ongoing tutelage by patient parents may explain how corvids have managed to achieve their smarts.

Journey to the Microcosmos:  Tardigrades: Chubby, Misunderstood, & Not Immortal

Images originally captured by Jam’s Germs

Thank you @airyearthgirl for inspiring me to gif these amazing lines

Therocephalians were a group of synapsids very closely related to – or possibly even ancestral to – the lineage leading to modern mammals. They were a diverse and successful group of carnivores during the latter half of the Permian, but suffered massively during the "Great Dying" mass extinction, with only a handful of representatives making it a few million years into the Triassic.

Tetracynodon darti was one of these rare Triassic therocephalian survivors, living in what is now South Africa around 251 million years ago. Only about 25cm long (~10"), it had slender limbs and strong claws that suggest it was a scratch-digger. Its long snout was lined with pointed teeth, and it was probably an active predator hunting by snapping its jaws at fast-moving prey like insects and smaller vertebrates.

Its combination of small size, burrow-digging habits, and unspecialized diet may be the reason it scraped through the Great Dying when most of its relatives didn't – but unfortunately it seems to have been a "dead clade walking", disappearing only a short way into early Triassic deposits.

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References:

Fontanarrosa, Gabriela, et al. "The manus of Tetracynodon (Therapsida: Therocephalia) provides evidence for survival strategies following the Permo-Triassic extinction." Journal of Vertebrate Paleontology 38.4 (2018): 1-13. https://doi.org/10.1080/02724634.2018.1491404

Sigurdsen, Trond, et al. "Reassessment of the morphology and paleobiology of the therocephalian Tetracynodon darti (Therapsida), and the phylogenetic relationships of Baurioidea." Journal of Vertebrate Paleontology 32.5 (2012): 1113-1134. https://www.researchgate.net/publication/254315180_Reassessment_of_the_Morphology_and_Paleobiology_of_the_Therocephalian_Tetracynodon_Darti_Therapsida_And_The_Phylogenetic_Relationships_of_Baurioidea

Wikipedia contributors. “Tetracynodon” Wikipedia, 21 Aug. 2024, https://en.wikipedia.org/wiki/Tetracynodon

Wikipedia contributors. “Therocephalia” Wikipedia, 01 Oct. 2024, https://en.wikipedia.org/wiki/Therocephalia

Not to self diagnose but something is wrong

*sticks my hand in your nucleus and swirls your dna around*

Stop the ban on blood donation of gay men

Women in STEM are just witches in white lab coats instead of black robes

art source: abigaillarson-Poisonous Plants irenhorrors-Drawlloween Laboratory