Xpandyourhorizons-blog - Xpand Your Horizons

Clovis wasn’t qualified, but worse may be yet to come

Why is Grassley still supporting Clovis despite evidence, acknowledged by his attorney, of Clovis' e-mail urging Papadopoulos' trip to Russia?

“Come on, folks. Let’s be honest. Clovis has zero scientific credentials for the chief scientist post to begin with. The former professor and right-wing radio host who has a doctorate in public administration is already a USDA staffer, but the investigative news site ProPublica could find no evidence he ever even took a graduate-level course in science. He believes human contributions to climate change are a hoax.

The chief scientist, who advises the government on scientific issues, has long been some leader in biochemistry, medicine, food nutrition, and ecosystem ecology. But Clovis has said the USDA under Trump would focus mostly on slashing regulations.“

Keep fighting back: climatetruth.org/standup

Doggerland, the Europe That Was (1015 x 1486)

New imaging study reveals how saturated fatty acids damage cells

In our increasingly health-conscious society, a new fad diet seems to pop up every few years. Atkins, Zone, Ketogenic, Vegetarian, Vegan, South Beach, Raw - with so many choices and scientific evidence to back each, it's hard to know what's healthy and what's not. One message, however, has remained throughout: saturated fats are bad.

A new Columbia University study reveals why.

While doctors, nutritionists and researchers have known for a long time that saturated fats contribute to some of the leading causes of death in the United States, they haven’t been able to determine how or why excess saturated fats, such as those released from lard, are toxic to cells and cause a wide variety of lipid-related diseases, while unsaturated fats, such as those from fish and olive oil, can be protective.

To find answers, Columbia researchers developed a new microscopy technique that allows for the direct tracking of fatty acids after they’ve been absorbed into living cells. The technique involves replacing hydrogen atoms on fatty acids with their isotope, deuterium, without changing their physicochemical properties and behavior like traditional strategies do. By making the switch, all molecules made from fatty acids can be observed inside living cells by an advanced imaging technique called stimulated Raman scattering (SRS) microscopy.

What the researchers found using this technique could have significant impact on both the understanding and treatment of obesity, diabetes and cardiovascular disease.

Published online December 1st in Proceedings of the National Academy of Sciences (PNAS), the team reports that the cellular process of building the cell membrane from saturated fatty acids results in patches of hardened membrane in which molecules are “frozen.” Under healthy conditions, this membrane should be flexible and the molecules fluidic.

“The behavior of saturated fatty acids once they’ve entered cells contributes to major and often deadly diseases,” Min said. “Visualizing how fatty acids are contributing to lipid metabolic disease gives us the direct physical information we need to begin looking for effective ways to treat them. Perhaps, for example, we can find a way to block the toxic lipid accumulation. We’re excited. This finding has the potential to really impact public health, especially for lipid related diseases.”

Yihui Shen et al, Metabolic activity induces membrane phase separation in endoplasmic reticulum, Proceedings of the National Academy of Sciences (2017). DOI: 10.1073/pnas.1712555114

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Cannabis Linked to Bipolar Symptoms in Young Adults

Cannabis use in youth is linked to bipolar symptoms in young adults, finds new research by the University of Warwick.

Researchers from Warwick Medical School found that adolescent cannabis use is an independent risk factor for future hypomania – periods of elated mood, over-active and excited behaviour, and reduced need for sleep that are often experienced as part of bipolar disorder, and have a significant impact on day-to-day life.

Led by Dr Steven Marwaha, a clinical academic Psychiatrist, the research analysed data from the Avon Longitudinal Study of Parents and Children and found that teenage cannabis use at least 2–3 times weekly is directly associated with suffering from symptoms of hypomania in later years.

There was a dose response relationship such that any use still increased the risk but less powerfully.

The Warwick research is the first to test the prospective association between adolescent cannabis use and hypomania in early adulthood, whilst controlling for important other factors that might explain this connection (e.g psychotic symptoms).

Full open access research for “Cannabis Use and Hypomania in Young People: A Prospective Analysis ” by Steven Marwaha, Catherine Winsper, Paul Bebbington, and Daniel Smith in Schizophrenia Bulleting. Published online November 28 2017 doi:10.1093/schbul/sbx158

An Asian elephant calf and its mother flee from a mob, throwing fiery balls of tar, in the Indian state of West Bengal.

2,000-Year-Old Killer Whale Geoglyph Found in Peru Desert

Archaeologists rediscovered a giant geoglyph of a killer whale, etched into a desert hillside in the remote Palpa region of southern Peru, after it had been lost to science for more than 50 years.

The 230-foot-long (70 meters) figure of an orca — considered a powerful, semimythical creature in ancient Peruvian lore — may be more than 2,000 years old, according to the researchers.

They said it may be one the oldest geoglyphs in the Palpa region, and older than those in the nearby Nazca region, which is famous for its vast collection of ancient ground markings — the Nazca Lines — that include animal figures, straight lines and geometrical shapes.

Archaeologist Johny Isla, the head of Peru’s Ministry of Culture in Ica province, which includes the Palpa and Nazca valleys, explained that he saw a single photograph of the orca pattern for the first time about four years ago. He’d seen it while researching studies of geoglyphs at the German Archaeological Institute in Bonn. Read more.