Oedema is swelling due to excess fluids in tissues.
In pitting oedema, pressing on the affected area leaves an indentation (that persists after removing the pressure). In non-pitting oedema, the area feels firm to touch and does not form indentations.
The excess fluid is mainly composed of water
Commonly caused by heart failure, venous insufficiency, or nephrotic syndrome
The excess fluid consists of water WITH protein and salts
Usually indicates a condition of the thyroid / lymphatic system
Different types:
Lymphoedema is due to a build-up of lymphatic fluid (e.g. due to a tumour blocking lymphatic flow / after removal of lymph nodes).
Myxoedema occurs in hypothyroidism and often affected the pretibial or periorbital area.
Angioedema is localised swelling of the skin and is usually due to allergic reactions. It typically affects the face, tongue, larynx, abdomen, arms, and legs. When the larynx is affected, it may affect breathing, which is an emergency!
Lipoedema is when fat accumulates in subcutaneous tissues - it usually affects the legs/buttocks and almost exclusively occurs in postpubertal females (not the same as cellulite!)
SHIP
Sulfasalazine & Sulfonamide Hydralazine Isoniazid Procainamide & Phenytoin
This is by no means a definitive list (they are many!) but these are some of the most common causes.
So Long Till Pinky, Here Comes The Thumb
Scaphoid
Lunate
Triquetrum
Pisiform
Hamate
Capitate
Trapezoid
Trapezium
(going anti-clockwise in this diagram)
Furosemide (and other loop diuretics) Aminoglycosides Vancomycin Quinine Aspirin
The renin-angiotensin system that helps regulate the constriction of blood vessels and blood pressure.
Alternatively:
Some Say Money Matters But My Brother Says Big Brains Matter More
Sooo… while studying the cranial nerves and their functions I came by this genius mnemonic and I just had to share it with you guys! :D
Some say money matters, but my brother says big boobs make more fun. [m = motoric, s = sensorial/sensitive, b = both]
N. olfactorius (s)
N. opticus (s)
N. oculomotorius (m)
N. trochlearis (m)
N. trigeminus (b)
N. abducens (m)
N. facialis (b)
N. vestibulocochlearis (s)
N. glossopharyngeus (b)
N. vagus (b)
N. accessorius (m)
N. hypoglossus (m)
(fun)
ACh acts on N2 receptors (ligand-gated Na+/K+ receptors)
Block Na+ channels that propagate nerve impulse - local anaesthetics (lidocaine), tetrodotoxin
Inhibit ACh release - tetanus toxin, botulinum toxin
Competitive antagonists - vecuronium
N2 agonists - suxamethonium
Flaccid paralysis
Only cleared by plasma cholinesterase
Reversible anticholinesterases - edrophonium, neostigmine, physostigmine
Block activity of AChE
Diagnose and treat myasthenia gravis and treat glaucoma respectively
Irreversible anticholinesterases - organophosphates (pesticides, nerve gases)
Long-lived flaccid paralysis
Treat with pralidoxime within 10 minutes - cleaves OP-AChE complex
Some Anatomists Like F*cking, Others Prefer S & M
Superior thyroid artery
Ascending pharyngeal artery
Lingual artery
Facial artery
Occipital artery
Posterior auricular artery
Superficial temporal artery
Maxillary artery
The superior thyroid, ascending pharyngeal, lingual and facial arteries are ANTERIOR branches.
The occipital and posterior auricular arteries are POSTERIOR branches.
The superficial temporal and maxillary arteries are TERMINAL branches.
“Some Anatomists Like F*cking, Others Prefer S & M”
is a mnemonic my professor just mentioned in class for the branches of the external carotid artery askjvb;askjbv;
U have no pot and you have no T but you have a long PR and a long QT
Low potassium causes:
U waves (small deflection immediately after T wave)
Flattened/inverted T waves
Prolonged PR interval
Apparent prolonged QT interval (due to fusion of T and U waves)
Also:
Increased P wave amplitude
Widespread ST depression
Morphine (+ anti-emetic)
Oxygen
Nitrate
Anti-platelet (aspirin, clopidogrel)
Thrombolytic (rtPA)
Primary angioplasty (PTCA)
Anticoagulant (heparin)
Beta-blocker
ACE inhibitor
Aspirin
Lipid-lowering (statin)
Lifestyle
Helpful mnemonic foe MI treatment.
Can - Citrate
I - Isocitrate
Keep - α-Ketoglutarate
Selling - Succinyl-CoA
Sex - Succinate
For - Fumarate
Money - Malate
Officer - Oxaloacetate
oh we are starting my favorite topic in biochemistry the tca cycle because whenever someone’s like :( it’s so hard to remember the intermediates :( i get to tell them about Can I Keep Selling Sex For Money Officer