photo source-The MacroClub Project (Myxomycetes)
Slime Mold
It’s well known that electric fields can guide the movements of skin cells, nudging them towards the site of an injury for instance. In fact, the human body generates an electric field that does this naturally. So researchers from the University of Freiburg in Germany set out to amplify the effect.
While it might not heal severe injuries with the speed of a Marvel superhero, it could radically reduce the time it takes for small tears and lacerations to recover.
For people with chronic wounds that take a long time to heal, such as in elderly folk, those with diabetes, or people with poor blood circulation, recovering quickly from frequent small, open cuts could be a literal lifesaver.
“Chronic wounds are a huge societal problem that we don’t hear a lot about,” says Maria Asplund, a bioelectronics scientist at the University of Freiburg and Chalmers University of Technology in Sweden.
“Our discovery of a method that may heal wounds up to three times faster can be a game changer for diabetic and elderly people, among others, who often suffer greatly from wounds that won’t heal.”
Continue Reading
Greetings, Tumblr community! 🧠💡 Let's engage in a comprehensive exploration of the sodium-potassium pump, dissecting its molecular intricacies and elucidating its critical role in cellular homeostasis.
Introduction:
The sodium-potassium pump, residing within the cellular membrane, is an adenosine triphosphate (ATP)-dependent transmembrane protein pivotal for maintaining ionic balance. Its primary function is to actively transport three sodium ions out of the cell while concurrently importing two potassium ions.
Functional Mechanism:
In terms of mechanistic precision, the sodium-potassium pump operates as an ATPase enzyme, utilizing the energy derived from ATP hydrolysis. This primary active transport process involves sequential conformational changes within the pump's structure.
The process commences with the binding of intracellular sodium ions to high-affinity sites on the pump. Subsequent phosphorylation, facilitated by ATP, induces conformational alterations that render the pump receptive to extracellular potassium ions. This triggers dephosphorylation, allowing potassium ions to be released intracellularly.
This orchestrated ion exchange serves to uphold the electrochemical gradient across the cellular membrane, establishing and preserving the resting membrane potential. In essence, the sodium-potassium pump is the architect of the delicate balance between sodium and potassium concentrations.
Physiological Significance:
The physiological ramifications of this meticulous ion transport extend to neuronal excitability and osmoregulation. By contributing to the establishment of the resting membrane potential, the pump plays a pivotal role in regulating action potentials and facilitating the propagation of nerve impulses.
Additionally, the pump actively participates in cellular volume control through osmoregulation. Its influence on water movement prevents cellular swelling or shrinkage, underscoring its significance in maintaining cellular integrity.
For those seeking empirical validation, consider consulting the following authoritative sources:
1. **Alberts B, Johnson A, Lewis J, et al.** Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. Section 11.3, The Plasma Membrane.
2. **Nelson DL, Cox MM.** Lehninger Principles of Biochemistry. 7th edition. New York: W.H. Freeman; 2017. Chapter 11, Active Transport and the Cytoskeleton.
3. **Lodish H, Berk A, Zipursky SL, et al.** Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Section 15.1, The Transport of Small Molecules Across Membranes.
Immerse yourself in the scientific intricacies of cellular dynamics with these foundational resources! 📚✨
Microcosms (2023)
linocuts on colored paper
(diatom species pictured: Stauroneis acuta, Pleurosigma inflatum, Triceratium pentacrinus, Actinoptychus heliopelta)
Root of Osmunda cinnamomea. The anatomy of woody plants. 1917.
Internet Archive
what the heck is blast
a tool for wizards