Spacewalk Friday: Installing A New "Parking Spot" On Station

The 2017 Atlantic Hurricane Season: What We Learned

The 2017 Atlantic hurricane season was among the top ten most active seasons in recorded history. Our experts are exploring what made this year particularly active and the science behind some of the biggest storms to date.

After a period of 12 years without a Category 3 or higher hurricane making landfall in the U.S., Hurricane Harvey made landfall over Texas as a Category 4 hurricane this August.

Harvey was also the biggest rainfall event ever to hit the continental U.S. with estimates more than 49 inches of rain.

Data like this from our Global Precipitation Measurement Mission, which shows the amount of rainfall from the storm and temperatures within the story, are helping scientists better understand how storms develop. 

The unique vantage point of satellites can also help first responders, and this year satellite data helped organizations map out response strategies during hurricanes Harvey, Irma and Maria. 
 

In addition to satellites, we use ground stations and aircraft to track hurricanes.

We also use the capabilities of satellites like Suomi NPP and others that are able to take nighttime views. In this instance, we were able to view the power outages in Puerto Rico. This allowed first responders to see where the location of impacted urban areas.

The combined effort between us, NOAA, FEMA and other federal agencies helps us understand more about how major storms develop, how they gain strength and how they affect us. 

To learn more about how we study storms, go to www.nasa.gov/Hurricanes.

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Say hello to globular cluster 47 Tucanae 👋

This glittery spray of ancient stars is about 16,700 light-years away from Earth toward the constellation Tucana. Globular clusters like this one are isolated star cities, home to hundreds of thousands of stars that are held together by their mutual gravity. And like the fast pace of cities, there's plenty of action in these stellar metropolises. The stars are in constant motion, orbiting around the cluster's center.

Past observations have shown that the heavyweight stars tend to crowd into the “downtown” core area, while lightweight stars reside in the less populated suburbs. But as heavyweight stars age, they rapidly lose mass, cool down and shut off their nuclear furnaces. After the purge, only the stars' bright, superhot cores – called white dwarfs – remain. This weight loss program causes the now lighter-weight white dwarfs to be nudged out of the downtown area through gravitational interactions with heftier stars.

Until these Hubble observations, astronomers had never seen the dynamic conveyor belt in action. The Hubble results reveal young white dwarfs amid their leisurely 40-million-year exodus from the bustling center of the cluster.

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Planets: As Seen by Voyager

The Voyager 1 and 2 spacecraft explored Jupiter, Saturn, Uranus and Neptune before starting their journey toward interstellar space. Here you’ll find some of those images, including “The Pale Blue Dot” – famously described by Carl Sagan – and what are still the only up-close images of Uranus and Neptune.

These twin spacecraft took some of the very first close-up images of these planets and paved the way for future planetary missions to return, like the Juno spacecraft at Jupiter, Cassini at Saturn and New Horizons at Pluto.

Jupiter

Photography of Jupiter began in January 1979, when images of the brightly banded planet already exceeded the best taken from Earth. They took more than 33,000 pictures of Jupiter and its five major satellites. 

Findings:

Erupting volcanoes on Jupiter's moon Io, which has 100 times the volcanic activity of Earth. 

Better understanding of important physical, geological, and atmospheric processes happening in the planet, its satellites and magnetosphere.

Jupiter's turbulent atmosphere with dozens of interacting hurricane-like storm systems.

Saturn

The Saturn encounters occurred nine months apart, in November 1980 and August 1981. The two encounters increased our knowledge and altered our understanding of Saturn. The extended, close-range observations provided high-resolution data far different from the picture assembled during centuries of Earth-based studies.

Findings:

Saturn’s atmosphere is almost entirely hydrogen and helium.

Subdued contrasts and color differences on Saturn could be a result of more horizontal mixing or less production of localized colors than in Jupiter’s atmosphere.

An indication of an ocean beneath the cracked, icy crust of Jupiter's moon Europa. 

Winds blow at high speeds in Saturn. Near the equator, the Voyagers measured winds about 1,100 miles an hour.

Uranus

The Voyager 2 spacecraft flew closely past distant Uranus, the seventh planet from the Sun. At its closest, the spacecraft came within 50,600 miles of Uranus’s cloud tops on Jan. 24, 1986. Voyager 2 radioed thousands of images and voluminous amounts of other scientific data on the planet, its moons, rings, atmosphere, interior and the magnetic environment surrounding Uranus.

Findings:

Revealed complex surfaces indicative of varying geologic pasts.

Detected 11 previously unseen moons.

Uncovered the fine detail of the previously known rings and two newly detected rings.

Showed that the planet’s rate of rotation is 17 hours, 14 minutes.

Found that the planet’s magnetic field is both large and unusual.

Determined that the temperature of the equatorial region, which receives less sunlight over a Uranian year, is nevertheless about the same as that at the poles.

Neptune

Voyager 2 became the first spacecraft to observe the planet Neptune in the summer of 1989. Passing about 3,000 miles above Neptune’s north pole, Voyager 2 made its closest approach to any planet since leaving Earth 12 years ago. Five hours later, Voyager 2 passed about 25,000 miles from Neptune’s largest moon, Triton, the last solid body the spacecraft had the opportunity to study.

Findings: 

Discovered Neptune’s Great Dark Spot

Found that the planet has strong winds, around 1,000 miles per hour

Saw geysers erupting from the polar cap on Neptune’s moon Triton at -390 degrees Fahrenheit

Solar System Portrait

This narrow-angle color image of the Earth, dubbed ‘Pale Blue Dot’, is a part of the first ever ‘portrait’ of the solar system taken by Voyager 1. 

The spacecraft acquired a total of 60 frames for a mosaic of the solar system from a distance of more than 4 billion miles from Earth and about 32 degrees above the ecliptic.

From Voyager’s great distance, Earth is a mere point of light, less than the size of a picture element even in the narrow-angle camera.

“Look again at that dot. That's here. That's home. That's us. On it everyone you love, everyone you know, everyone you ever heard of, every human being who ever was, lived out their lives.” - Carl Sagan

Both spacecraft will continue to study ultraviolet sources among the stars, and their fields and particles detectors will continue to search for the boundary between the Sun's influence and interstellar space. The radioisotope power systems will likely provide enough power for science to continue through 2025, and possibly support engineering data return through the mid-2030s. After that, the two Voyagers will continue to orbit the center of the Milky Way.

Learn more about the Voyager spacecraft HERE.

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Do not go where the path may lead, go instead where there is no path and leave a trail.  —Ralph Waldo Emerson 

Solar System: Things to Know This Week

10 Tools for the Armchair Astronaut, or  How to Explore the Solar System from Home

At this very moment, spacecraft are surveying the solar system, from Mars, to Saturn, to Pluto and beyond. Now you can ride along to see the latest discoveries from deep space. For this week's edition of 10 Things, we've assembled a toolkit of 10 essential resources for the desktop astronaut.  

1. It's Like Facebook, but for Planets

Or is it more of a Hitchhiker's Guide to the Solar System? Whatever one calls it, our planets page offers quick rundowns, as well as in-depth guides, for all the major bodies in the solar system. Explore from the sun all the way to the Oort Cloud.

+ Peruse the planets + See how objects in the solar system stack up against each other

2. Keep Your Eyes on This One

If you still haven't tried Eyes on the Solar System, you're missing out. This free, downloadable simulation app lets you tour the planets and track the past, current and future positions of spacecraft--all in 3D. Eyes on the Solar System uses real NASA data to help you take a virtual flight across both space and time.

+ Prepare for departure

3. Dateline: Deep Space

With so much exploration underway, discoveries and new insights into the solar system come at a pace that borders on bewildering. NASA is rewriting the textbooks, literally, on a regular basis. Relax, though: there are several easy ways to stay up to date with what's happening in space.

+ See the latest headlines + Stay connected on social media: Twitter, Facebook, Instagram + Find more top NASA social media accounts

4. Space? There's an App for That

NASA offers phone and tablet apps for star gazing, pictures, news, 3D tours, satellite tracking, live NASA TV and many other kinds of info.

+ Start downloading + See other cool apps

5. A (Very) Long Distance Call

We’re in constant communication with spacecraft all over the solar system. The Deep Space Network is a global network of giant antenna dishes that makes it possible. With this online app, you can learn how it works -- and even see which spacecraft are phoning home right now.

+ Deep Space Network (DSN) Now

6. Collect 'Em All

Spacecraft 3D is an augmented reality (AR) application that lets you learn about and interact with a variety of spacecraft that are used to explore our solar system, study Earth and observe the universe. Print out the AR target and your camera will do the rest, making the spacecraft appear in 3D right in front of you. Learn more about these robotic explorers as they pop up on your desk, in your hand, or on your dog's head.

+ Download Spacecraft 3D + See more cool 3-D resources from NASA

7. Ever Wanted to Drive a Mars Rover?

This site will give you a 3D look at the Mars Curiosity rover, along with some of the terrain it has explored. It will even let you take the controls.

+ Experience Curiosity

8. More E-Ticket Attractions

But wait, there's more. NASA offers a variety of other fascinating (and free) online experiences, all based on actual data from real missions. Here are a few to explore:

+ Mars Trek + Vesta Trek + Moon Trek

9. The Universe Is Our Classroom

Studying the solar system makes for a compelling route into learning and teaching science, engineering and math. We have some great places to start.

+ Find resources for teachers + Build your own solar system with your classroom

10. Bring It on Home

After you've toured the far reaches of the solar system, you can always come home again. When you have spent time studying the harsh conditions on our neighboring planets, the charms of a unique paradise come into sharp focus, the place we call Earth.

+ Watch a real-time video feed from Earth orbit + See a daily global view of our planet from a million miles away + Hold the earth in your hands with the Earth Now mobile app

Discover more lists of 10 things to know about our solar system HERE.

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Worlds That Will Make You Believe Star Wars is Real

The fantastical planets in Star Wars preceded our discovery of real planets outside our solar system…but fiction isn’t too far from the facts. When we send our spacecraft into the solar system and point our telescopes beyond, we often see things that seem taken right out of the Star Wars universe.

Is there a more perfect time than May the 4th to compare real worlds to the ones depicted in Star Wars? 

Probably not...so here are a few:

Mimas

Saturn’s moon, Mimas, has become known as the "Death Star" moon because of how its 80-mile wide Herschel crater creates a resemblance to the Imperial battle station, especially when seen in this view from our Cassini spacecraft. 

Kepler-452b

The most recently revealed exoplanet dubbed as Earth’s bigger, older cousin, Kepler-452b, might make a good stand-in for Coruscant — the high tech world seen in several Star Wars films whose surface is encased in a single, globe-spanning city. Kepler-452b belongs to a star system 1.5 billion years older than Earth’s! That would give any technologically adept species more than a billion-year jump ahead of us.

CoRoT-7b

At 3,600 degrees Fahrenheit, CoRoT-7B is a HOT planet. Discovered in 2010 with France’s CoRoT satellite, it’s some 480 light-years away, and has a diameter 70% larger than Earth’s, with nearly five times the mass. Possibly the boiled-down remnant of a Saturn-sized planet, its orbit is so tight that its star looms much larger in its sky than our sun appears to us, keeping its sun-facing surface molten!  This scorching planet orbiting close to its star could be a good analog for planet Mustafar from Star Wars. 

Kepler-16b

Luke Skywalker’s home planet, Tatooine, is said to possess a harsh, desert environment, swept by sandstorms as it roasts under the glare of twin suns. Real exoplanets in the thrall of two or more suns are even harsher! Kepler-16b was the Kepler telescope’s first discovery of a planet in a “circumbinary” orbit (a.k.a, circling both stars, as opposed to just one, in a double star system). This planet, however, is likely cold, about the size of Saturn, and gaseous, though partly composed of rock.

OGLE-2005-BLG-390

Fictional Hoth is a frozen tundra that briefly serves as a base for the hidden Rebel Alliance. It’s also the nickname of real exoplanet OGLE-2005-BLG-390, a cold super-Earth whose surface temperature clocks in at minus 364 degrees Fahrenheit.

Kepler-22b

Kepler-22b, analog to the Star Wars planet Kamino…which was the birthplace of the army of clone soldiers, is a super-Earth that could be covered in a super ocean. The jury is still out on Kepler-22b’s true nature; at 2.4 times Earth’s radius, it might even be gaseous. But if the ocean world idea turns out to be right, we can envision a physically plausible Kamino-like planet.

Gas Giants

Gas giants of all stripes populate the real exoplanet universe; in Star Wars, a gas giant called Bespin is home to a “Cloud City” actively involved in atmospheric mining. Mining the atmospheres of giant gas planets is a staple of science fiction. We too have examined the question, and found that gases such as helium-3 and hydrogen could theoretically be extracted from the atmospheres of Uranus and Neptune. 

Exomoons

Endor, the forested realm of the Ewoks, orbits a gas giant. Exomoon detection is still in its infancy for scientists on Earth. However, a possible exomoon (a moon circling a distant planet) was observed in 2014 via microlensing. It will remain unconfirmed, however, since each microlensing event can be seen only once.

May the 4th be with you!

Discover more about exoplanets here: https://exoplanets.jpl.nasa.gov/

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What Scientists Are Learning from the Eclipse

While millions of people in North America headed outside to watch the eclipse on Aug. 21, 2017, hundreds of scientists got out telescopes, set up instruments, and prepared balloon launches – all so they could study the Sun and its complicated influence on Earth.

Total solar eclipses happen about once every 18 months somewhere in the world, but the August eclipse was rare because of its long path over land. The total eclipse lasted more than 90 minutes over land, from when it first reached Oregon to when it left the U.S. in South Carolina.

This meant that scientists could collect more data from land than during most eclipses, giving us new insight into our world and the star that powers it.

A moment in the Sun’s atmosphere

During a total solar eclipse, the Sun’s outer atmosphere, the corona, is visible from Earth. It’s normally too dim to see next to the Sun’s bright face, but, during an eclipse, the Moon blocks out the Sun, revealing the corona.

Image Credit: Peter Aniol, Miloslav Druckmüller and Shadia Habbal

Though we can study parts of the corona with instruments that create artificial eclipses, some of the innermost regions of the corona are only visible during total solar eclipses. Solar scientists think this part of the corona may hold the secrets to some of our most fundamental questions about the Sun: Like how the solar wind – the constant flow of magnetized material that streams out from the Sun and fills the solar system – is accelerated, and why the corona is so much hotter than the Sun’s surface below.  

Depending on where you were, someone watching the total solar eclipse on Aug. 21 might have been able to see the Moon completely obscuring the Sun for up to two minutes and 42 seconds. One scientist wanted to stretch that even further – so he used a pair of our WB-57 jets to chase the path of the Moon’s shadow, giving their telescopes an uninterrupted view of the solar corona for just over seven and half minutes.

These telescopes were originally designed to help monitor space shuttle launches, and the eclipse campaign was their first airborne astronomy project!

These scientists weren’t the only ones who had the idea to stretch out their view of the eclipse: The Citizen CATE project (short for Continental-America Telescopic Eclipse) did something similar, but with the help of hundreds of citizen scientists. 

Citizen CATE included 68 identical small telescopes spread out across the path of totality, operated by citizen and student scientists. As the Moon’s shadow left one telescope, it reached the next one in the lineup, giving scientists a longer look at the way the corona changes throughout the eclipse.

After accounting for clouds, Citizen CATE telescopes were able to collect 82 minutes of images, out of the 93 total minutes that the eclipse was over the US. Their images will help scientists study the dynamics of the inner corona, including fast solar wind flows near the Sun’s north and south poles.

The magnetized solar wind can interact with Earth’s magnetic field, causing auroras, interfering with satellites, and – in extreme cases – even straining our power systems, and all these measurements will help us better understand how the Sun sends this material speeding out into space.

Exploring the Sun-Earth connection

Scientists also used the eclipse as a natural laboratory to explore the Sun’s complicated influence on Earth.

High in Earth’s upper atmosphere, above the ozone layer, the Sun’s intense radiation creates a layer of electrified particles called the ionosphere. This region of the atmosphere reacts to changes from both Earth below and space above. Such changes in the lower atmosphere or space weather can manifest as disruptions in the ionosphere that can interfere with communication and navigation signals.

One group of scientists used the eclipse to test computer models of the ionosphere’s effects on these communications signals. They predicted that radio signals would travel farther during the eclipse because of a drop in the number of energized particles. Their eclipse day data – collected by scientists spread out across the US and by thousands of amateur radio operators – proved that prediction right.

In another experiment, scientists used the Eclipse Ballooning Project to investigate the eclipse’s effects lower in the atmosphere. The project incorporated weather balloon flights from a dozen locations to form a picture of how Earth’s lower atmosphere – the part we interact with and which directly affects our weather – reacted to the eclipse. They found that the planetary boundary layer, the lowest part of Earth’s atmosphere, actually moved closer to Earth during the eclipse, dropped down nearly to its nighttime altitude.

A handful of these balloons also flew cards containing harmless bacteria to explore the potential for contamination of other planets with Earth-born life. Earth’s stratosphere is similar to the surface of Mars, except in one main way: the amount of sunlight. But during the eclipse, the level of sunlight dropped to something closer to what you’d expect to see on Mars, making this the perfect testbed to explore whether Earth microbes could hitch a ride to the Red Planet and survive. Scientists are working through the data collected, hoping to build up better information to help robotic and human explorers alike avoid carrying bacterial hitchhikers to Mars.

Image: The small metal card used to transport bacteria.

Finally, our EPIC instrument aboard NOAA’s DSCOVR satellite provided awe-inspiring views of the eclipse, but it’s also helping scientists understand Earth’s energy balance. Earth’s energy system is in a constant dance to maintain a balance between incoming radiation from the Sun and outgoing radiation from Earth to space, which scientists call the Earth’s energy budget. The role of clouds, both thick and thin, is important in their effect on energy balance.

Like a giant cloud, the Moon during the total solar eclipse cast a large shadow across a swath of the United States. Scientists know the dimensions and light-blocking properties of the Moon, so they used ground- and space-based instruments to learn how this large shadow affects the amount of sunlight reaching Earth’s surface, especially around the edges of the shadow. Measurements from EPIC show a 10% drop in light reflected from Earth during the eclipse (compared to about 1% on a normal day). That number will help scientists model how clouds radiate the Sun’s energy – which drives our planet’s ocean currents, seasons, weather and climate – away from our planet.

For even more eclipse science updates, stay tuned to nasa.gov/eclipse.

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All-Star Moments in Space Communications and Navigation

How do we get information from missions exploring the cosmos back to humans on Earth? Our space communications and navigation networks – the Near Space Network and the Deep Space Network – bring back science and exploration data daily.

Here are a few of our favorite moments from 2024.

1. Hip-Hop to Deep Space

The stars above and on Earth aligned as lyrics from the song “The Rain (Supa Dupa Fly)” by hip-hop artist Missy Elliott were beamed to Venus via NASA’s Deep Space Network. Using a 34-meter (112-foot) wide Deep Space Station 13 (DSS-13) radio dish antenna, located at the network’s Goldstone Deep Space Communications Complex in California, the song was sent at 10:05 a.m. PDT on Friday, July 12 and traveled about 158 million miles from Earth to Venus — the artist’s favorite planet. Coincidentally, the DSS-13 that sent the transmission is also nicknamed Venus!

NASA's PACE mission transmitting data to Earth through NASA's Near Space Network.

2. Lemme Upgrade You

Our Near Space Network, which supports communications for space-based missions within 1.2 million miles of Earth, is constantly enhancing its capabilities to support science and exploration missions. Last year, the network implemented DTN (Delay/Disruption Tolerant Networking), which provides robust protection of data traveling from extreme distances. NASA’s PACE (Plankton, Aerosol, Cloud, ocean Ecosystem) mission is the first operational science mission to leverage the network’s DTN capabilities. Since PACE’s launch, over 17 million bundles of data have been transmitted by the satellite and received by the network’s ground station.

A collage of the pet photos sent over laser links from Earth to LCRD and finally to ILLUMA-T (Integrated LCRD Low Earth Orbit User Modem and Amplifier Terminal) on the International Space Station. Animals submitted include cats, dogs, birds, chickens, cows, snakes, and pigs.

3. Who Doesn’t Love Pets?

Last year, we transmitted hundreds of pet photos and videos to the International Space Station, showcasing how laser communications can send more data at once than traditional methods. Imagery of cherished pets gathered from NASA astronauts and agency employees flowed from the mission ops center to the optical ground stations and then to the in-space Laser Communications Relay Demonstration (LCRD), which relayed the signal to a payload on the space station. This activity demonstrated how laser communications and high-rate DTN can benefit human spaceflight missions.

4K video footage was routed from the PC-12 aircraft to an optical ground station in Cleveland. From there, it was sent over an Earth-based network to NASA’s White Sands Test Facility in Las Cruces, New Mexico. The signals were then sent to NASA’s Laser Communications Relay Demonstration spacecraft and relayed to the ILLUMA-T payload on the International Space Station.

4. Now Streaming

A team of engineers transmitted 4K video footage from an aircraft to the International Space Station and back using laser communication signals. Historically, we have relied on radio waves to send information to and from space. Laser communications use infrared light to transmit 10 to 100 times more data than radio frequency systems. The flight tests were part of an agency initiative to stream high-bandwidth video and other data from deep space, enabling future human missions beyond low-Earth orbit.

The Near Space Network provides missions within 1.2 million miles of Earth with communications and navigation services.

5. New Year, New Relationships

At the very end of 2024, the Near Space Network announced multiple contract awards to enhance the network’s services portfolio. The network, which uses a blend of government and commercial assets to get data to and from spacecraft, will be able to support more missions observing our Earth and exploring the cosmos. These commercial assets, alongside the existing network, will also play a critical role in our Artemis campaign, which calls for long-term exploration of the Moon.

On Monday, Oct. 14, 2024, at 12:06 p.m. EDT, a SpaceX Falcon Heavy rocket carrying NASA’s Europa Clipper spacecraft lifts off from Launch Complex 39A at NASA’s Kennedy Space Center in Florida.

6. 3, 2, 1, Blast Off!

Together, the Near Space Network and the Deep Space Network supported the launch of Europa Clipper. The Near Space Network provided communications and navigation services to SpaceX’s Falcon Heavy rocket, which launched this Jupiter-bound mission into space! After vehicle separation, the Deep Space Network acquired Europa Clipper’s signal and began full mission support. This is another example of how these networks work together seamlessly to ensure critical mission success.

Engineer Adam Gannon works on the development of Cognitive Engine-1 in the Cognitive Communications Lab at NASA’s Glenn Research Center.

7. Make Way for Next-Gen Tech

Our Technology Education Satellite program organizes collaborative missions that pair university students with researchers to evaluate how new technologies work on small satellites, also known as CubeSats. In 2024, cognitive communications technology, designed to enable autonomous space communications systems, was successfully tested in space on the Technology Educational Satellite 11 mission. Autonomous systems use technology reactive to their environment to implement updates during a spaceflight mission without needing human interaction post-launch.

A first: All six radio frequency antennas at the Madrid Deep Space Communication Complex, part of NASA’s Deep Space Network (DSN), carried out a test to receive data from the agency’s Voyager 1 spacecraft at the same time.

8. Six Are Better Than One

On April 20, 2024, all six radio frequency antennas at the Madrid Deep Space Communication Complex, part of our Deep Space Network, carried out a test to receive data from the agency’s Voyager 1 spacecraft at the same time. Combining the antennas’ receiving power, or arraying, lets the network collect the very faint signals from faraway spacecraft.

Here’s to another year connecting Earth and space.  

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Around the World 100,000 Times

The International Space Station is a microgravity laboratory in which an international crew of six people live and work while traveling at a speed of five miles per second (or 17,500 miles per hour), orbiting Earth every 90 minutes.

Monday, May 16, marks the International Space Station’s 100,000th orbit!

That’s more than 2,643,342,240 miles traveled! Which is also like 10 round trips to Mars, OR nearly the distance to Neptune!

The space station has been in orbit for over 17 years, and during that time, over 1,922 research investigations have been performed. More than 1,200 scientific results publications have been produced as a result. 

Important studies like the VEGGIE experiment, which is working to grow plants in microgravity, and the Twin’s Study, which is studying the impacts of microgravity on the human body, are helping us on our journey to Mars. Using this unique orbiting laboratory as a place to conduct research is helping us learn important things for future deep space missions. 

There have even been 222 different people that have visited the space station. This includes the current crew that is working and living on orbit. 

Did you know that the space station is the third brightest object in the sky? If you know when and where to look up, you can spot it on your own! Find out when and where to look up HERE. 

On Snapchat? Watch today’s Live Story to discover more about the orbiting laboratory and get a tour of the station! You can also add ‘nasa’ on Snapchat to get a regular dose of space. 

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Using the Power of Space to Fight Cancer

From cancer research to DNA sequencing, the International Space Space is proving to be an ideal platform for medical research. But new techniques in fighting cancer are not confined to research on the space station. Increasingly, artificial intelligence is helping to "read" large datasets. And for the past 15 years, these big data techniques pioneered by our Jet Propulsion Laboratory have been revolutionizing biomedical research.

Microgravity Research on Space Station

On Earth, scientists have devised several laboratory methods to mimic normal cellular behavior, but none of them work exactly the way the body does. Beginning more than 40 years ago aboard Skylab and continuing today aboard the space station, we and our partners have conducted research in the microgravity of space.  In this environment, in vitro cells arrange themselves into three-dimensional groupings, or aggregates. These aggregates more closely resemble what actually occurs in the human body. Cells in microgravity also tend to clump together more easily, and they experience reduced fluid shear stress -- a type of turbulence that can affect their behavior. The development of 3D structure and enhanced cell differentiation seen in microgravity may help scientists study cell behavior and cancer development in models that behave more like tissues in the human body.

In addition, using the distinctive microgravity environment aboard the station, researchers are making further advancements in cancer therapy. The process of microencapsulation was investigated aboard the space station in an effort to improve the Earth-based technology. Microencapsulation is a technique that creates tiny, liquid-filled, biodegradable micro-balloons that can serve as delivery systems for various compounds, including specific combinations of concentrated anti-tumor drugs. For decades, scientists and clinicians have looked for the best ways to deliver these micro-balloons, or microcapsules, directly to specific treatment sites within a cancer patient, a process that has the potential to revolutionize cancer treatment.

A team of scientists at Johnson Space Center used the station as a tool to advance an Earth-based microencapsulation system, known as the Microencapsulation Electrostatic Processing System-II (MEPS-II), as a way to make more effective microcapsules. The team leveraged fluid behavior in microgravity to develop a new technique for making these microcapsules that would be more effective on Earth. In space, microgravity brought together two liquids incapable of mixing on Earth (80 percent water and 20 percent oil) in such a way that spontaneously caused liquid-filled microcapsules to form as spherical, tiny, liquid-filled bubbles surrounded by a thin, semipermeable, outer membrane. After studying these microcapsules on Earth, the team was able to develop a system to make more of the space-like microcapsules on Earth and are now performing activities leading to FDA approval for use in cancer treatment.  

In addition, the ISS National Laboratory managed by the Center for the Advancement of Science in Space (CASIS) has also sponsored cancer-related investigations.  An example of that is an investigation conducted by the commercial company Eli Lilly that seeks to crystallize a human membrane protein involved in several types of cancer together with a compound that could serve as a drug to treat those cancers. 

"So many things change in 3-D, it's mind-blowing -- when you look at the function of the cell, how they present their proteins, how they activate genes, how they interact with other cells," said Jeanne Becker, Ph.D., a cell biologist at Nano3D Biosciences in Houston and principal investigator for a study called Cellular Biotechnology Operations Support Systems: Evaluation of Ovarian Tumor Cell Growth and Gene Expression, also known as the CBOSS-1-Ovarian study. "The variable that you are most looking at here is gravity, and you can't really take away gravity on Earth. You have to go where gravity is reduced." 

Crunching Big Data Using Space Knowledge

Our Jet Propulsion Laboratory often deals with measurements from a variety of sensors -- say, cameras and mass spectrometers that are on our spacecraft. Both can be used to study a star, planet or similar target object. But it takes special software to recognize that readings from very different instruments relate to one another.

There’s a similar problem in cancer research, where readings from different biomedical tests or instruments require correlation with one another. For that to happen, data have to be standardized, and algorithms must be “taught” to know what they’re looking for.

Because space exploration and cancer research share a similar challenge in that they both must analyze large datasets to find meaning, JPL and the National Cancer Institute renewed their research partnership to continue developing methods in data science that originated in space exploration and are now supporting new cancer discoveries.

JPL’s methods are leading to the development of a single, searchable network of cancer data that researcher can work into techniques for the early diagnosis of cancer or cancer risk. In the time they’ve worked together, the two organizations’ efforts have led to the discovery of six new Food and Drug Administration-approved cancer biomarkers. These agency-approved biomarkers have been used in more than 1 million patient diagnostic tests worldwide.

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