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-My sun and stars!

-Moon of my life!

5 things that may surprise you about the Moon

…In honor of International Observe the Moon Night

October 28th is International Observe the Moon Night, a worldwide, public celebration of lunar science and exploration held annually since 2010 thanks to our Lunar Reconnaissance Orbiter (LRO) mission team and partners. One day each year, everyone on Earth is invited to observe and learn about the Moon together, and to celebrate the cultural and personal connections we all have with our planet’s nearest neighbor.

Here are 5 things that might surprise you about the Moon.

1. There has been a spacecraft there for 100 lunar days

In October 2017, LRO celebrates one hundred days of collecting scientific data at the Moon. One hundred Moon days. From our perspective on Earth, one lunar day is one full phase cycle, or about 29.5 Earth days. That’s 100 opportunities to observe changes from night to day, photograph the surface at different Sun angles, measure rising and falling temperatures, study the way certain chemicals react to the daily light and temperature cycle, and increase our understanding of the Moon as a dynamic place.

2. You can still see the paths left by Apollo astronauts’ boot prints and rovers

Much of the lunar surface is covered in very fine dust. When Apollo astronauts landed on the Moon, the descent stage engine disturbed the dust and produced a distinct bright halo around the lunar module. As astronauts moved around, their tracks exposed the darker soil underneath, creating distinct trails that we know, thanks to LRO, are still visible today. The Moon has no atmosphere, so there is no wind to wipe away these tracks.

3. The Moon has tattoos!

Observations from LRO show mysterious patterns of light and dark that are unique to the Moon. These lunar swirls look painted on, like the Moon got ‘inked.’ Lunar swirls, like these imaged at Reiner Gamma by LRO, are found at more than 100 locations across the lunar surface. Lunar swirls can be tens of miles across and appear in groups or as isolated features. 

Researchers think these patterns form in places where there’s still a remnant of the Moon’s magnetic field. There are still many competing theories about how swirls form, but the primary idea is that the local magnetic field deflects the energetic particles in the solar wind, so there’s not as much weathering of the surface. The magnetically shielded areas would then look brighter than everything around them.

4. There were once active volcanoes, that shaped what we see now

Early astronomers named the large dark spots that we see on the near side of the Moon “maria,” Latin for “seas,” because that’s what they thought they were. We now know that the dark spots are cooled lava, called basalt, formed from ancient volcanic eruptions. The Moon’s volcanoes are no longer active, but their past shapes the Moon that we see today. The Moon doesn’t have large volcanoes like ones in Hawaii, but it does have smaller cones and domes. 

Other small features derived from volcanic activity include rivers of dried lava flows, like the ones visible in this image of Vallis Schroteri taken by LRO, and dark areas formed from eruptive volcanoes that spewed fire. For many years, scientists thought the Moon’s volcanic activity died out long ago, but there’s some evidence for relatively “young” volcanism, suggesting that the activity gradually slowed down instead of stopping abruptly.

5. Anyone, anywhere can participate in International Observe the Moon Night.  

How to celebrate International Observe the Moon Night

Attend an event –  See where events are happening near you by visiting http://observethemoonnight.org

Host an event – Call up your neighbors and friends and head outdoors – no special equipment is needed. Let us know how you celebrated by registering your event!

Don’t let cloudy weather get you down! Observe the Moon in a variety of ways from the comfort of indoors – View stunning lunar vistas through images and videos, or explore the Moon on your own with QuickMap or Moon Trek

Join the worldwide conversation with #ObserveTheMoon on Twitter, Instagram and Facebook

For regular Moon-related facts, updates and science, follow @NASAMoon on Twitter

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com.

Cracking eggshell nanostructure: New discovery could have important implications for food safety

How is it that fertilized chicken eggs manage to resist fracture from the outside, while at the same time, are weak enough to break from the inside during chick hatching? It’s all in the eggshell’s nanostructure, according to a new study led by McGill University scientists.

The findings, reported today in Science Advances, could have important implications for food safety in the agro-industry.

Birds have benefited from millions of years of evolution to make the perfect eggshell, a thin, protective biomineralized chamber for embryonic growth that contains all the nutrients required for the growth of a baby chick. The shell, being not too strong, but also not too weak (being “just right” Goldilocks might say), is resistant to fracture until it’s time for hatching.

But what exactly gives bird eggshells these unique features?

To find out, Marc McKee’s research team in McGill’s Faculty of Dentistry, together with Richard Chromik’s group in Engineering and other colleagues, used new sample-preparation techniques to expose the interior of the eggshells to study their molecular nanostructure and mechanical properties.

Read more.

New process allows 3-D printing of nanoscale metal structures

Synthesizing organic scaffolds that contain metal ions enables 3-D printing of metallic structures that are orders of magnitude smaller than previously possible

For the first time, it is possible to create complex nanoscale metal structures using 3-D printing, thanks to a new technique developed at Caltech.

The process, once scaled up, could be used in a wide variety of applications, from building tiny medical implants to creating 3-D logic circuits on computer chips to engineering ultralightweight aircraft components. It also opens the door to the creation of a new class of materials with unusual properties that are based on their internal structure. The technique is described in a study that will be published in Nature Communications on February 9.

In 3-D printing – also known as additive manufacturing – an object is built layer by layer, allowing for the creation of structures that would be impossible to manufacture by conventional subtractive methods such as etching or milling. Caltech materials scientist Julia Greer is a pioneer in the creation of ultratiny 3-D architectures built via additive manufacturing. For instance, she and her team have built 3-D lattices whose beams are just nanometers across – far too small to be seen with the naked eye. These materials exhibit unusual, often surprising properties; Greer’s team has created exceptionally lightweight ceramics that spring back to their original shape, spongelike, after being compressed.

Greer’s group 3-D prints structures out of a variety of materials, from ceramics to organic compounds. Metals, however, have been difficult to print, especially when trying to create structures with dimensions smaller than around 50 microns, or about half the width of a human hair.

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Gene discovery unlocks mysteries to our immunity

"It's exciting to consider that C6 has existed for more than 500 million years, preserved and passed down from simple organisms all the way to humans. But only now are we gaining insights into its importance."

Australia’s national science agency CSIRO has identified a new gene that plays a critical role in regulating the body’s immune response to infection and disease.

The discovery could lead to the development of new treatments for influenza, arthritis and even cancer.

The gene, called C6orf106 or “C6”, controls the production of proteins involved in infectious diseases, cancer and diabetes. The gene has existed for 500 million years, but its potential is only now understood.

Continue Reading.

(via MIT researchers turn water into ‘calm’ computer interfaces)

…The Tangible Media Group demonstrated a way to precisely transport droplets of liquid across a surface back in January, which it called “programmable droplets.” The system is essentially just a printed circuit board, coated with a low-friction material, with a grid of copper wiring on top. By programmatically controlling the electric field of the grid, the team is able to change the shape of polarizable liquid droplets and move them around the surface. The precise control is such that droplets can be both merged and split.

Moving on from the underlying technology, the team is now focused on showing how we might leverage the system to create, play and communicate through natural materials…

A battery that eats CO2

By Khai Trung Le

A new type of battery developed by researchers at MIT could be made partly from carbon dioxide captured from power plants. Rather than attempting to convert carbon dioxide to specialized chemicals using metal catalysts, which is currently highly challenging, this battery could continuously convert carbon dioxide into a solid mineral carbonate as it discharges.

The battery is made from lithium metal, carbon, and an electrolyte that the researchers designed. While still based on early-stage research and far from commercial deployment, the new battery formulation could open up new avenues for tailoring electrochemical carbon dioxide conversion reactions, which may ultimately help reduce the emission of the greenhouse gas to the atmosphere.

Currently, power plants equipped with carbon capture systems generally use up to 30 percent of the electricity they generate just to power the capture, release, and storage of carbon dioxide. Anything that can reduce the cost of that capture process, or that can result in an end product that has value, could significantly change the economics of such systems, the researchers say.

Betar Gallant, Assistant Professor of Mechanical Engineering at MIT, said, ‘Carbon dioxide is not very reactive. Trying to find new reaction pathways is important.’Ideally, the gas would undergo reactions that produce something worthwhile, such as a useful chemical or a fuel. However, efforts at electrochemical conversion, usually conducted in water, remain hindered by high energy inputs and poor selectivity of the chemicals produced.

The team looked into whether carbon-dioxide-capture chemistry could be put to use to make carbon-dioxide-loaded electrolytes — one of the three essential parts of a battery — where the captured gas could then be used during the discharge of the battery to provide a power output.

The team developed a new approach that could potentially be used right in the power plant waste stream to make material for one of the main components of a battery. By incorporating the gas in a liquid state, however, Gallant and her co-workers found a way to achieve electrochemical carbon dioxide conversion using only a carbon electrode. The key is to preactivate the carbon dioxide by incorporating it into an amine solution.

‘What we’ve shown for the first time is that this technique activates the carbon dioxide for more facile electrochemistry,’ Gallant says. ‘These two chemistries — aqueous amines and nonaqueous battery electrolytes — are not normally used together, but we found that their combination imparts new and interesting behaviors that can increase the discharge voltage and allow for sustained conversion of carbon dioxide.’

The battery is made from lithium metal, carbon, and an electrolyte that the researchers designed. While still based on early-stage research and far from commercial deployment, the new battery formulation could open up new avenues for tailoring electrochemical carbon dioxide conversion reactions, which may ultimately help reduce the emission of the greenhouse gas to the atmosphere.

@neysastudies

Toxic ‘zombie’ cells seen for 1st time in Alzheimer’s

A type of cellular stress known to be involved in cancer and aging has now been implicated, for the first time, in Alzheimer’s disease. UT Health San Antonio faculty researchers reported the discovery in the journal Aging Cell.

The team found that the stress, called cellular senescence, is associated with harmful tau protein tangles that are a hallmark of 20 human brain diseases, including Alzheimer’s and traumatic brain injury. The researchers identified senescent cells in postmortem brain tissue from Alzheimer’s patients and then found them in postmortem tissue from another brain disease, progressive supranuclear palsy.

Cellular senescence allows the stressed cell to survive, but the cell may become like a zombie, functioning abnormally and secreting substances that kill cells around it. “When cells enter this stage, they change their genetic programming and become pro-inflammatory and toxic,” said study senior author Miranda E. Orr, Ph.D., VA research health scientist at the South Texas Veterans Health Care System, faculty member of the Sam and Ann Barshop Institute for Longevity and Aging Studies, and instructor of pharmacology at UT Health San Antonio. “Their existence means the death of surrounding tissue.”

Improvements in brain structure and function

The team confirmed the discovery in four types of mice that model Alzheimer’s disease. The researchers then used a combination of drugs to clear senescent cells from the brains of middle-aged Alzheimer’s mice. Such drugs are called senolytics. The drugs used by the San Antonio researchers are dasatinib, a chemotherapy medication that is U.S. Food and Drug Administration-approved to treat leukemia, and quercetin, a natural flavonoid compound found in fruits, vegetables and some beverages such as tea.

After three months of treatment, the findings were exciting. “The mice were 20 months old and had advanced brain disease when we started the therapy,” Dr. Orr said. “After clearing the senescent cells, we saw improvements in brain structure and function. This was observed on brain MRI studies (magnetic resonance imaging) and postmortem histology studies of cell structure. The treatment seems to have stopped the disease in its tracks.”

“The fact we were able to treat very old mice and see improvement gives us hope that this treatment might work in human patients even after they exhibit symptoms of a brain disease,” said Nicolas Musi, M.D., study first author, who is Professor of Medicine and Director of the Sam and Ann Barshop Institute at UT Health San Antonio. He also directs the VA-sponsored Geriatric Research, Education and Clinical Center (GRECC) in the South Texas Veterans Health Care System.

Typically, in testing an intervention in Alzheimer’s mice, the therapy only works if mice are treated before the disease starts, Dr. Musi said.

Tau protein accumulation is responsible

In Alzheimer’s disease, patient brain tissue accumulates tau protein tangles as well as another protein deposit called amyloid beta plaques. The team found that tau accumulation was responsible for cell senescence. Researchers compared Alzheimer’s mice that had only tau tangles with mice that had only amyloid beta plaques. Senescence was identified only in the mice with tau tangles.

In other studies to confirm this, reducing tau genetically also reduced senescence. The reverse also held true. Increasing tau genetically increased senescence.

Importantly, the drug combination reduced not only cell senescence but also tau tangles in the Alzheimer’s mice. This is a drug treatment that does not specifically target tau, but it effectively reduced the tangle pathology, Dr. Orr said.

“When we looked at their brains three months later, we found that the brains had deteriorated less than mice that received placebo control treatment,” she said. “We don’t think brain cells actually grew back, but there was less loss of neurons, less brain ventricle enlargement, improved cerebral blood flow and a decrease in the tau tangles. These drugs were able to clear the tau pathology.”

Potentially a therapy to be tested in humans

“This is the first of what we anticipate will be many studies to better understand this process,” Dr. Musi said. “Because these drugs are approved for other uses in humans, we think a logical next step would be to start pilot studies in people.”

The drugs specifically target—and therefore only kill—the senescent cells. Because the drugs have a short half-life, they are cleared quickly by the body and no side effects were observed.

Dasatinib is an oral medication. The mice were treated with the combination every other week. “So in the three months of treatment, they only received the drug six times,” Dr. Orr said. “The drug goes in, does its job and is cleared. Senescent cells come back with time, but we expect that it would be possible to take the drug again and be cleared out again. That’s a huge benefit—it wouldn’t be a drug that people would have to take every day.”

Dosage and frequency in humans would need to be determined in clinical trials, she said.

Next, the researchers will study whether cell senescence is present in traumatic brain injury. TBI is a brain injury that develops tau protein accumulation and is a significant cause of disability in both military and non-military settings, Dr. Orr said.

AI-based method could speed development of specialized nanoparticles

A new technique developed by MIT physicists could someday provide a way to custom-design multilayered nanoparticles with desired properties, potentially for use in displays, cloaking systems, or biomedical devices. It may also help physicists tackle a variety of thorny research problems, in ways that could in some cases be orders of magnitude faster than existing methods.

The innovation uses computational neural networks, a form of artificial intelligence, to “learn” how a nanoparticle’s structure affects its behavior, in this case the way it scatters different colors of light, based on thousands of training examples. Then, having learned the relationship, the program can essentially be run backward to design a particle with a desired set of light-scattering properties – a process called inverse design.

The findings are being reported in the journal Science Advances, in a paper by MIT senior John Peurifoy, research affiliate Yichen Shen, graduate student Li Jing, professor of physics Marin Soljacic, and five others.

Read more.

Carrying and releasing nanoscale cargo with ‘nanowrappers’

This holiday season, scientists at the Center for Functional Nanomaterials (CFN) – a U.S. Department of Energy Office of Science User Facility at Brookhaven National Laboratory – have wrapped a box of a different kind. Using a one-step chemical synthesis method, they engineered hollow metallic nanosized boxes with cube-shaped pores at the corners and demonstrated how these “nanowrappers” can be used to carry and release DNA-coated nanoparticles in a controlled way. The research is reported in a paper published on Dec. 12 in ACS Central Science, a journal of the American Chemical Society (ACS).

“Imagine you have a box but you can only use the outside and not the inside,” said co-author Oleg Gang, leader of the CFN Soft and Bio Nanomaterials Group. “This is how we’ve been dealing with nanoparticles. Most nanoparticle assembly or synthesis methods produce solid nanostructures. We need methods to engineer the internal space of these structures.”

“Compared to their solid counterparts, hollow nanostructures have different optical and chemical properties that we would like to use for biomedical, sensing, and catalytic applications,” added corresponding author Fang Lu, a scientist in Gang’s group. “In addition, we can introduce surface openings in the hollow structures where materials such as drugs, biological molecules, and even nanoparticles can enter and exit, depending on the surrounding environment.”

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