Thejoyofscience - This Is For All The Nerdy Girls

Vaccine Infographic by Leon Farrant.

I often speak with patients who tell me that they do not wish to be vaccinated because they do not see the point, that it is a farce, that it can cause autism (it does not), despite educating and informing them of the reasons behind it. 

In the same way that people who did not grow up during the great wars of the mid-twentieth century have little frame of reference as to what the toll of total war can be, neither can a newer generation of people who have never seen the effects of polio, smallpox, and measles ravage humanity. For many people in the developed world, these are just distant, faded memories captured in the pages of medical textbooks. 

I sincerely hope that the understanding of why we vaccinate does not become lost over time, that people need not fall victim to these preventable diseases; otherwise, the suffering, the challenges, and the research that went into developing these vaccines were all for nothing.

Monochrome image of a victorian butterfly tongue captured by Gregg Kleinberg with a Paxcam microscope camera under the microscope at 400x.

(Image: U. Müeller)

New neurons (in green) are guided to the neocortex  - responsible for controlling language and movement - not by glial cells, but by a protein called reelin.

Journal reference: Neuron, DOI: 10.1016/j.neuron.2011.01.003

chappelle-“remember bitch you clicked on my face”

of course i did...that’s cuz you used to be funny

Usual interstitial pneumonia

It has the loose fibroblastic balls (pink balls) next to relatively normal lung parenchyma (thin septae) and a bronchiole (the blueish wrinkly thing)

(Via pulmonary pathology)

Medical lung is like… impossible. COP. DAD. DIP. NSIP. BOOP. POOP. SCHMOOP. No idea. It all looks the same to me.

ANTI-BARFING SPIKES.

This is why they have such a problem with plastic bags. It’s because the unique structure of their esophagus makes it so that they can’t get rid of them.

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Colonial rotifers showing eyespots and corona, magnification 200x - 500x. Ralph Grimm.

I read case files on dogs with serology positive for Ehrlichia co-infections all day today. Sooo many CBCs, blood chem panels, and cytology reports from clin path. All the things. And at the end of the day, I was like

Urine sediment from a 6 year-old, male-intact, Rottweiler.  The patient has a multi-year history of recurrent urinary tract infections.  He recently presented to his primary care veterinarian for being unable to urinate.  Radiographs showed no bladder stones, but a penile ultrasound showed many obstructing the urethra.  The dog was then referred for surgery to relieve the obstruction…

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The surgeons were kind enough to snag us some urine!  The urine was full of these hexagonal crystals….consistent with cystine crystals!  Yes, the amino acid cystine.  In addition, there were all shapes of sperms (see them swimming in the background!) along with many inflammatory cells and some bacteria.

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Diagnosis:  Cystine crystalluria.  This is a very rare occurrence in veterinary medicine!  Such patient’s often have a genetic defect in the metabolism or transport of cystine, allowing the amino acid to accumulate in blood.  Once it filters into urine, cystine will polymerize into crystals and sometimes form stones.  Cystine stones do not obstruct x-rays…hence they cannot be found on standard radiographs (termed radiolucent).  The patient is recovering well following surgery, and may require a special diet to help with his disease.

Ms. Holly Aaron, Dr. Karen Dehnert, Dr. Scott Laughlin, and Dr. Carolyn Bertozzi

University of California, Berkeley, California, USA Specimen: Fucosylated glycans in a zebrafish embryo. Technique: Confocal microscopy