Mitochondria are primarily known as the powerhouse of the cell. However, these cellular organelles are required not only for providing energy: Professor Konstanze Winklhofer and her group at the Faculty of Medicine at Ruhr University Bochum, Germany, recently discovered that mitochondria play an important role in signal transduction in innate immune pathways.
They regulate a signaling pathway that helps to eliminate pathogens, but can cause damage through inflammation upon overactivation. The research team published their findings in the EMBO Journal.
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my friend is studying for the mcat and was just trying to explain to me about heat transfer and she said ‘you know, like the reason you get cold when you go outside on a freezing day is that your tiny human body is trying to warm up the entire universe’ and i think that’s the best thing i have ever heard
“Here I am, trying to stop my grandma from taking amoxicillin for headaches.”
Let’s use antibiotics safely and responsibly, please.
Dear scientists,
Please, for the love of God, please, make your papers more understandable.
Fuck you
Sincerely,
A college student on the verge of tears
Antibodies are the secreted form of B-lymphocyte receptors and are a part of adaptive immunity, but how are these proteins formed?
Above is a diagram illustrating Paul Ehlrich’s Side Chain Theory of Antibody Formation. Ehlrich proposed that immunoglobulin molecules, a fundamental component of adaptive immunity, served as membrane bound proteins that bound to particular threats, similarly to the former “key in lock” view of enzymes in catalyzing biological reactions. Ehrlich also suggested that the action of binding a pathogenic molecule to the receptor would generate a signal to stimulate the production of more receptors of the same specificity. These “side chains” that were added on would then break off from the cell surface and become what we call antibodies.
We now know, however, that soluble immunoglobulin receptors are specially manufactured to be secreted as antibody, rather than just “breaking off” of the lymphocyte, even though they have the same specificity as their membrane-bound counterparts.
Plz reblog, I need to know I'm not alone in this.
Women in STEM are just witches in white lab coats instead of black robes
art source: abigaillarson-Poisonous Plants irenhorrors-Drawlloween Laboratory