For Decades, Scientists Have Been Capitalizing Off Discoveries Made From Henrietta Lacks’ Family’s

Vaccine Infographic by Leon Farrant.

I often speak with patients who tell me that they do not wish to be vaccinated because they do not see the point, that it is a farce, that it can cause autism (it does not), despite educating and informing them of the reasons behind it. 

In the same way that people who did not grow up during the great wars of the mid-twentieth century have little frame of reference as to what the toll of total war can be, neither can a newer generation of people who have never seen the effects of polio, smallpox, and measles ravage humanity. For many people in the developed world, these are just distant, faded memories captured in the pages of medical textbooks. 

I sincerely hope that the understanding of why we vaccinate does not become lost over time, that people need not fall victim to these preventable diseases; otherwise, the suffering, the challenges, and the research that went into developing these vaccines were all for nothing.

Journey to the Microcosmos-  The Complicated Legacy of Lynn Margulis 

Images originally captured by Jam’s Germs

Thumbs Up For Science

The cover of the legendary journal Nature from February 1879, featuring this thumb microscope, yours for the low, low price of three pounds. 

(via Ptak Science Books, which you should really check out)

“What’s that on the beach?!" 

Monterey Bay beachcombers and divers were treated to a huge bloom of salps this weekend! Salps are gelatinous filter-feeders that drift with and feed in the plankton. Wind and waves sometimes blow these open-ocean emissaries onshore by the thousands, a feast for fishes, invertebrates—and for the eyes of curious naturalists!

There were several species of salps in this weekend’s bloom, including these in the genus Salpa. Salps do not sting—in fact, they’re more closely related to fishes and people than they are to other "jellies”! The brown/orange orb is the salp’s gut. Pumping muscle bands push water from one end of the animal to the other through an internal plankton-pasta strainer.

Salps have an incredibly successful reproductive strategy, allowing them to explode in numbers when conditions are right. Ready? Here we go: Salps can be found as solos, or as a chain of dozens of individuals attached together. Same species, two different body morphs. The solos produce the chain asexually, and the individuals in the chain are all clones. 

OK, still with us? The next part is a doozy: A young chain is female, and each female clone produces another solo salp from an egg that is fertilized by older male chains. The older male chains are female chains that changed sex as they aged—this is called sequential hermaphroditism. This whole process allows salps to produce new generations at an incredible rate, to take advantage of fleeting oceanic conditions. Phew, we did it!

Salps are thought to have an outsized effect on the flow of nutrients in the ocean’s food web. Because their fecal pellets sink, salp poop delivers vital nutrition from the ocean surface to the deep seafloor, and helps take carbon from the atmosphere to the deep, which helps regulate the planet’s climate. Spent salps from these huge blooms become food for countless organisms throughout the water column. Certain deep sea communities may even depend on these ephemeral feasts to survive in the desert of the abyssal plain, according to research by our colleagues at the Monterey Bay Aquarium Research Institute (MBARI).

This weekend’s salp bloom is a jiggly reminder of the vast community of gelatinous drifters—the gelata—that drift in the open ocean, connecting the surface to the deep and adjusting the Earth’s energy flow, unseen by most until a chance encounter on the shore.

Photo: Charles Schrammel Gif: Alison Smith

Steering Stem Cells with Magnets

Magnets could be a tool for directing stem cells’ healing powers to treat conditions such as heart disease or vascular disease.

By feeding stem cells tiny particles made of iron oxide, scientists at Emory and Georgia Tech can use magnets to attract the cells to a particular location in the body after intravenous injection.

The results are published online in the journal Small and will appear in an upcoming issue.

Human Adipose Derived Mesenchymal Stem Cells

More…

Behold the Gastric Rainbow. Sounds gross, but it’s actually beautiful. This cross-section of a mouse intestine is labeled with a spectrum of fluorescent molecules. From the green and magenta digestive enzyme-producing cells to the red mucus-secreting cells, this is one of the most dynamic areas in the mammalian body: Each cell is replaced by another every 3-5 days.

(via The Scientist Magazine)

Contest Entries: Hypatia of Alexandria

My favorite Female Scientist by Drziggystardust

Mathematician, philosopher, astronomer- Mostly known for her work in mathematics because she is the first well documented woman in the field. Her life and work were so important that many scholars agree that her brutal murder by religious zealots marks the end of the Classical Antiquity era, at the very least her death marked the downfall of intellectual life in Alexandria.    

Right lateral thoracic wall mass from a 10 year-old, female-spayed, Golden Retriever.  Approximately six months ago the owner noticed a small, firm swelling on the patient’s right chest.  No doubt it grew with time, as it finally got large enough for the owner to become truly concerned!  The patient is clinically healthy otherwise.

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The most prominent feature on the cytology were these gorgeous globules of magenta, streaming material!  In fact, the entire slide was imbued with this color when you looked at it without a microscope.  The substance is most likely matrix produced by cancer cells.  Matrix of this color is commonly observed in chrondrosarcomas.  Occasional malignant spindle-shaped cells were found imbedded in the matrix.

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Diagnosis:  Chondrosarcoma.  Well , that’s the most likely diagnosis given the location and appearance of the neoplastic cells and matrix!  Other possibilities include a myxosarcoma (which produces a mucous like material!) or osteosarcoma (malignant primary bone tumor).  Chondrosarcomas are often regionally invasive but rarely metastasize.  If the owner is on board with a chest wall resection, the patient will have  a good prognosis :-)