Credit To Jurassic Park As A Fictional Work, They At Least Added The DNA From An Unrelated Species To

Credit to Jurassic Park as a fictional work, they at least added the DNA from an unrelated species to the existing DNA, regardless of how unrelated it was.

I mean, it's stupid to use frog DNA but at least they STARTED with the original creature.

I've thought since the late 2010s, start with what you have, see how it can be combined to create the most complete sample and extrapolate the rest to try and create a decent approximation of enough genetic data to grow the sex cells.

People who have a better grasp of biology could certainly improve on this rough idea, I don't know how to create the conditions to grow the egg and I'm not convinced doing so in a live surrogate as with cloning is entirely possible for a long-extinct mammal.

To anyone who follows me, I don't care about nor trust Colossal Biosciences anymore (The people behind the "Wooly Mice"). They have proven themselves to be headline-chasing grifters after this latest stunt. They are claiming to have de-extincted *Aenocyon dirus*, aka the Dire Wolf, by editing just 20 genes from the the DNA of a Grey Wolf (*Canis lupus*) to make this thing:

To Anyone Who Follows Me, I Don't Care About Nor Trust Colossal Biosciences Anymore (The People Behind

If it wasn't clear from their scientific names, Grey Wolves and Dire Wolves aren't remotely related to one another aside from being Canids, despite what pop culture like Game of Thrones would have you believe. If they did look like each other, it would have had to be via convergent evolution, as they only shared a common ancestor over 5 million years ago.

To Anyone Who Follows Me, I Don't Care About Nor Trust Colossal Biosciences Anymore (The People Behind

This distinction, however, isn't found in the publicized articles about this so-called resurrected Dire Wolf and makes their claim that they brought the Dire Wolf back by simply editing *20* genes from the genome of a Grey Wolf laughable. A Dire Wolf would have shared more in common genetically with a Maned Wolf (*Chrysocyon brachyurus*) or Bush Dog (*Speothos venaticus*) than it would with a Grey Wolf.

To Anyone Who Follows Me, I Don't Care About Nor Trust Colossal Biosciences Anymore (The People Behind

Bottom line, don't fall for whatever this company is trying to tell you. If the Dire Wolf were to be brought back, it wouldn't be via something like this, and certainly wouldn't *look* like this. If you want an idea as to how a real Dire Wolf would look like in life, here is some fantastic paleoart by artist Mauricio Antón:

To Anyone Who Follows Me, I Don't Care About Nor Trust Colossal Biosciences Anymore (The People Behind

Addendum: I seem to have partially miscalculated Dire Wolf genetics. They were not closer to Maned Wolves or Bush Dogs, but they were still not closely related to Grey Wolves. They were basal members of Canini, related to canids like Jackals (genus Lupulella) but distinct from them. I am sorry for this misinformation in my attempt to correct other misinformation. My main point, however, is still correct.

More Posts from M-p-lebrush and Others

2 months ago
We're Supposed To Be Unfeeling. How Many Times Do I Have To Tell You To Snuff Out Your Heart?

We're supposed to be unfeeling. How many times do I have to tell you to snuff out your heart?

Beak is less obvious with this one, but it does take the upper part of his skull.

Ha! I Knew It! Your Words Are No Match For The Pure Strength Of Our Hearts, Bound Together As One.

Ha! I knew it! Your words are no match for the pure strength of our hearts, bound together as one.


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3 months ago

Frankly, being 21 and attending high school sounds pretty darn weird unless you're a member of staff.

“No? Why? Because I’m a vampire?” “No… Actually, pretending you’re 21 and attending high school for eighty years is a little weird, man.”

1 month ago

Just going to yeet nonsense into the void so it stops taking up room in my head:

12 remembers Clara at the end of his life, is overcome by such a strong impression (around 2 and a half series) of girlboss energy that he returns to what is best described as earliest known (in-universe) settings. There's possibly thoughts about Missy there too.

13 can be very inconsistent in opinions, I like that she genuinely seems to hate the Master though. Other New Who doctors were all, "Noooo..... you were my best friend, you can be good!" This is good, but 13 thinks the one version of the Master she had gotten through to just ran away and abandoned her.

Throw in a Master who's seemingly regressed to all-out mania as a coping mechanism after getting hurt as Missy, and their dynamic makes more sense.

The comment regarding de-cloaking the Master around the Nazis was still seriously fucked up. I genuinely wonder what the writers of that era were on half the time.

Flux was pretty fun, though.


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2 months ago

Granny Weatherwax in the Streets. Nanny Ogg in the Sheets.

2 months ago

any computer people wanna explain how the hell this works

Any Computer People Wanna Explain How The Hell This Works
Any Computer People Wanna Explain How The Hell This Works

it wont let me do shit bc i apparently have 81 gigs of apps clogging my c drive, but my largest app is 0.4gb?????? its not system applications either because system is its own segment of storage. wadda hell are you talking about


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1 month ago

Holy s***, almost forgot Kane Chronicles, Perry Johanson, Magnus Chase et. all. Riordan is a very good author to binge read. He's not perfect for being inclusive but he sure does try. Maybe too much. If you've only read Peter Johnson and Heroes of Olympus, you're missing out. I much prefer Kane Chronicles and Magnus Chase, and Daughter of the Deep is very good.

Erm, trying to think of more fantasy for teens and young adults is hard. That's all I have for stuff you can binge read.

The House of Secrets trilogy and Spiderwick Chronicles are both good, Narnia is alright if you can endure the racism and hot devil analogues in your area.

The Power of Five series is quite good for something on the darker end, but there's an uncomfortable use of colonialist language in the second book and it's not the easiest to get through.

Tolkien's shorter stories; such as those in Tales From the Perilous Realm and his Letters from Father Christmas are very good.

As far as other things you can binge read, A Series of Unfortunate Events and All the Wrong Questions are two separate stories from the same universe penned by Lemony Snicket.

Jeeves and Wooster is great, especially with the short stories. It massively improved my writing around the end of high school, though the humour not be for you.

I'd recommend not binge reading the Sherlock Holmes short stories because they can be quite a pain to get through. The full length ones are much better but regardless, Conan Doyle likes to get sidetracked and after forcing my way through the full volume of stories I can understand where his hate was coming from.

Just don't try Bond unless you're an edgy teen, preferably a boy. The George Smiley books by John le Carré are far better spy stories and they're not as well, they're not as outdated by even the standards of their own time period. From Russia with Love is pretty good but doesn't hold a candle to Tinker Tailor Soldier Spy. Just a general recommendation, I never tried binge reading le Carré. Alex Rider by Anthony Horowitz is a decent Bond alternative for less edgy teenage boys.

The Hunger Games is still as relevant as ever. Read it. Then read the other two books by Suzanne Collins. She's a good writer.

Misc books I recommend include Moriarty by Anthony Horowitz, The History of Bees by Maja Lunde, The Watchmaker of Filigree Street by Natasha Pulley, Ash Mistry is great if you like Riordan and want a similar take with Indian belief (though I've only had the pleasure of reading the first book), Good Omens if you can get a pre-loved copy is mostly Pratchett and if you read enough Discworld you can tell who he wrote (I miss the four other horsemen of the apocalypse, why aren't they in the show).

Give narrative history a shot as a way to learn history, try the other work authors you like have made and sorry for the long ass post.

Have Watson bashing on Sherlock before Holmes even got addicted to opium:

Holy S***, Almost Forgot Kane Chronicles, Perry Johanson, Magnus Chase Et. All. Riordan Is A Very Good
Holy S***, Almost Forgot Kane Chronicles, Perry Johanson, Magnus Chase Et. All. Riordan Is A Very Good

Ya know what? Even before JK Rowling outed herself as a substandard primate, I wasn't a big fan. Harry Potter is the least bingeable fantasy series I've read.

Lord of the Rings? Perfect for binge reading.

Discworld? Streaming services envy the variety.

Harry Potter? Tonal whiplash like there's no tomorrow. Went from kids books to being for edgy teens that don't want to be embarrassed yet.

At least How to Train Your Dragon doesn't try to change demographic that quickly. It actually matures over the series and takes time to transition, instead of just switching to a different style out of nowhere.

Soz for the ramble in tags.

1 month ago

Ya know what? Even before JK Rowling outed herself as a substandard primate, I wasn't a big fan. Harry Potter is the least bingeable fantasy series I've read.

Lord of the Rings? Perfect for binge reading.

Discworld? Streaming services envy the variety.

Harry Potter? Tonal whiplash like there's no tomorrow. Went from kids books to being for edgy teens that don't want to be embarrassed yet.

At least How to Train Your Dragon doesn't try to change demographic that quickly. It actually matures over the series and takes time to transition, instead of just switching to a different style out of nowhere.

Soz for the ramble in tags.


Tags
3 months ago

There's a lot more. "Oh damn, oh damn oh damn oh damn," in the whole thing, but yes.

The doctor recognizing the master is like Dr. doofenshmirtz recognizing Perry the platypus. Idk how to explain it but it’s the same deal. Y’all know what I mean.

4 weeks ago

Let's get you in the box, fish. It might be a squeeze but I'm sure you can manage.

put me in the 1 inch x 1 inch x 1 inch box coach!!! I'm all fired up, I'm ready!!!!!

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m-p-lebrush - Untitled and Incoherent
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